胃肠道寄生虫感染对绵羊血液铜含量和血红蛋白水平的影响。
The effect of gastrointestinal parasitism on blood copper and hemoglobin levels in sheep.
作者信息
Adogwa A, Mutani A, Ramnanan A, Ezeokoli C
机构信息
School of Veterinary Medicine, Faculty of Medical Sciences, The University of the West Indies, St. Augustine, West Indies.
出版信息
Can Vet J. 2005 Nov;46(11):1017-21.
Endoparasitism is a problem in Trinidad, as it is in most tropical countries. Parasite infection has been suspected to contribute to the pathogenesis of swayback disease (which is also prevalent in Trinidad), but the mode of action has not been clearly defined, although it has been suggested that parasites interfere with the absorption of copper from the gastrointestinal tract. The objectives of the study were to assess the effect of endoparasitism on blood copper levels and hemoglobin (Hb) concentration in sheep in Trinidad. Copper was administered intramuscularly to parasite infected and noninfected animals. The results showed that parasitism has a depressing effect on blood copper and Hb levels, even when administered parenterally. It is concluded that parasitism can aggravate existing hypocupremia and possibly influence the expression of swayback disease.
内寄生虫病在特立尼达是个问题，在大多数热带国家也是如此。寄生虫感染一直被怀疑与摇摆病（在特立尼达也很普遍）的发病机制有关，但其作用方式尚未明确界定，尽管有人认为寄生虫会干扰胃肠道对铜的吸收。本研究的目的是评估内寄生虫病对特立尼达绵羊血铜水平和血红蛋白（Hb）浓度的影响。对感染寄生虫和未感染寄生虫的动物进行肌肉注射铜。结果表明，即使通过非肠道途径给药，寄生虫感染仍会对血铜和Hb水平产生抑制作用。得出的结论是，寄生虫感染会加重现有的低铜血症，并可能影响摇摆病的表现。
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