Frandsen J C
Am J Vet Res. 1982 Nov;43(11):1951-3.
Subclinical infections by the intestinal nematode Trichostrongylus colubriformis were established in 7 pigmy goats by inoculating each with 4,000 infective larvae 5 days/week for 18 weeks. At the start of the 14th week, 3 of the goats were orally inoculated daily with 10,000 sporulated oocytes of the coccidium Eimeria christenseni for 6 days, producing subclinical infections. During selected weeks, the goats were placed in metabolism cages to monitor feed consumption and collect orts, feces, and urine. Samples of rib, vertebra, and tibia were removed at time of death, on day 126. The superimposition of the coccidial infections on the nematode infections did not affect apparent ash, nitrogen, organic matter, or dry matter digestibilities; balances of nitrogen or phosphorus; serum copper or zinc concentrations; liveweights or feed conversion efficiencies. Mean calcium balances remained positive, although they were reduced during the first week of the superimposed coccidial infections. The mineralization of the matrix of the tibia and 4th lumbar vertebra was less in the goats with the superimposed coccidial infections than in those infected only with nematodes. Presence of the superimposed infections was associated with a decrease in the mean moisture and lipid contents of the tibia.
通过每周5天、持续18周给7只侏儒山羊每只接种4000条感染性幼虫，使其建立了肠道线虫捻转血矛线虫的亚临床感染。在第14周开始时，给其中3只山羊每天口服10000个球虫克里斯滕艾美耳球虫的孢子化卵囊，持续6天，从而产生亚临床感染。在选定的几周内，将山羊置于代谢笼中，以监测采食量并收集剩余饲料、粪便和尿液。在第126天死亡时采集肋骨、椎骨和胫骨样本。球虫感染叠加在线虫感染上并未影响表观灰分、氮、有机物或干物质消化率；氮或磷的平衡；血清铜或锌浓度；体重或饲料转化效率。尽管在叠加球虫感染的第一周平均钙平衡有所降低，但仍保持正值。与仅感染线虫的山羊相比，叠加球虫感染的山羊胫骨和第四腰椎椎体基质的矿化程度较低。叠加感染的存在与胫骨平均水分和脂质含量的降低有关。
