Lisowska-Myjak Barbara
Katedra i Zakład Biochemii i Chemii Klinicznej, Akademia Medyczna w Warszawie.
Ginekol Pol. 2005 Jul;76(7):571-9.
The use of licit and illicit drugs and exposure to other xenobiotic agents during pregnancy is common. These substances are known to have adverse effects on the pregnancy and fetus; however information on fetal exposure is sparse due to the lack of an appropriate measure of exposure. Meconium analysis is a new method for identifying in utero exposure of infants to a number of illicit and legal drugs, alcohol, nicotine, heavy metals, pesticides, congenital infections. It's testing is non-invasive, highly accurate and able to detect prior exposure in utero during 12-40 weeks of gestation. This has implications for toxicology to develop improved methods to identify exposed infants.
孕期使用合法及非法药物以及接触其他外源性物质的情况很常见。已知这些物质会对妊娠和胎儿产生不良影响；然而，由于缺乏合适的暴露测量方法，关于胎儿暴露的信息很少。胎粪分析是一种用于识别婴儿子宫内暴露于多种非法和合法药物、酒精、尼古丁、重金属、农药、先天性感染的新方法。其检测是非侵入性的，高度准确，并且能够检测出妊娠12 - 40周期间子宫内的既往暴露情况。这对毒理学发展改进方法以识别暴露婴儿具有重要意义。
