Neumann M P, Eng M H, Rholl K S, Swedo G J, Meranze S G
Department of Laboratory Medicine and Pathology, Alexandria Hospital, Virginia 22304.
Acta Cytol. 1992 Jul-Aug;36(4):527-8.
A case of disseminated histoplasmosis diagnosed by percutaneous needle biopsy cytology is reported. The patient presented with fever and pancytopenia. Computed tomography (CT) revealed retroperitoneal lymphadenopathy. Cytology smears prepared from a CT-guided screw needle biopsy of one of the lymph nodes showed numerous histiocytes with intracytoplasmic yeast forms consistent with Histoplasma capsulatum. Fungal cultures prepared from additional needle biopsy material confirmed the diagnosis. This case illustrates the utility of needle biopsy in the evaluation of radiographically detected retroperitoneal lymphadenopathy and in the rapid diagnosis of infectious disease in certain clinical settings.
报告了一例经皮针吸活检细胞学诊断的播散性组织胞浆菌病病例。患者表现为发热和全血细胞减少。计算机断层扫描（CT）显示腹膜后淋巴结肿大。对其中一个淋巴结进行CT引导下螺旋针吸活检制备的细胞学涂片显示，有大量组织细胞，其胞浆内酵母样形态与荚膜组织胞浆菌一致。从额外的针吸活检材料中进行的真菌培养证实了诊断。该病例说明了针吸活检在评估影像学检查发现的腹膜后淋巴结肿大以及在某些临床情况下快速诊断传染病方面的实用性。
