Powers C N
Department of Pathology, SUNY Health Science Center at Syracuse 13210, USA.
Clin Microbiol Rev. 1998 Apr;11(2):341-65. doi: 10.1128/CMR.11.2.341.
This review explores the role of the cytopathology laboratory in the detection and presumptive identification of microorganisms. Sample procurement by exfoliation, abrasion, and aspiration techniques, as well as a variety of cytopreparatory and staining methods, is reviewed. Emphasis is placed on the utility of fine-needle aspiration as a rapid, safe, and cost-effective diagnositic procedure. The role of rapid interpretation and specimen triage is also discussed. Cytomorphologic features and staining characteristics are presented for a spectrum of microorganisms potentially encountered in the cytopathology laboratory. Pitfalls in diagnosis and the usefulness of special stains and ancillary techniques are also evaluated. The importance of communication, collaboration, and clinical correlation is stressed.
本综述探讨了细胞病理学实验室在微生物检测和初步鉴定中的作用。回顾了通过脱落、刮擦和抽吸技术采集样本，以及各种细胞制备和染色方法。重点强调了细针抽吸作为一种快速、安全且经济高效的诊断程序的实用性。还讨论了快速解读和标本分流的作用。介绍了细胞病理学实验室中可能遇到的一系列微生物的细胞形态学特征和染色特性。还评估了诊断中的陷阱以及特殊染色和辅助技术的实用性。强调了沟通、协作和临床相关性的重要性。
