Noël S, Guillaume M P, Telerman-Toppet N, Cogan E
Department of Internal Medicine, Hôpital Universitaire Brugmann, Free University of Brussels, Belgium.
Acta Neurol Belg. 1992;92(3):148-56.
Hemichorea and parkinsonism are unusual manifestations of cerebral toxoplasmosis in patients with AIDS. We here describe two such cases and we reviewed extensively the literature (through computer searches using MEDLINE) for other reported instances. In our patients, unlike the other neurological symptoms, the response of the movement disorders to anti-toxoplasmosis therapy was delayed and only partial. We demonstrate that tetrabenazine is a valuable additional symptomatic treatment for choreic movements in one of our patients. We emphasize that, among patients suffering from AIDS, particularly in countries with high prevalence of toxoplasmosis, the occurrence of movement disorders should first suggest the diagnosis of cerebral toxoplasmosis.
偏身舞蹈症和帕金森症是艾滋病患者脑弓形虫病的不常见表现。我们在此描述两例此类病例，并通过使用医学文献数据库（MEDLINE）进行计算机检索，广泛回顾了其他已报道的病例。在我们的患者中，与其他神经症状不同，运动障碍对抗弓形虫病治疗的反应延迟且仅部分有效。我们证明，丁苯那嗪对我们其中一名患者的舞蹈样动作是一种有价值的辅助对症治疗。我们强调，在艾滋病患者中，尤其是在弓形虫病高发国家，运动障碍的出现应首先提示脑弓形虫病的诊断。
