[从获得性免疫缺陷综合征（艾滋病）患者唾液中分离出弓形虫]
[Isolation of Toxoplasma gondii from the saliva of patients with acquired immunodeficiency syndrome (AIDS)].
作者信息
Amato Neto V, Braz L M, Jamra L M, Higaki Y, Pasternak J
机构信息
Laboratório de Investigação Médica-Parasitologia, Hospital das Clínicas, Faculdade de Medicina, Universidade de São Paulo.
出版信息
Rev Hosp Clin Fac Med Sao Paulo. 1990 Jul-Aug;45(4):171-2.
Toxoplasma gondii has been found in saliva of patients with toxoplasmosis. We tried to isolate parasites in saliva in patients with AIDS. As it is known, the finding of antitoxoplasma antibodies is not useful for diagnosis of cerebral abscess in toxoplasmosis occurring in AIDS patients in Brazil where 90% or more adults have serological evidence of past infection with Toxoplasma gondii. In 26 patients with AIDS, including six with tomographical evidence suggesting cerebral abscess caused by Toxoplasma gondii, no parasites were found in the saliva by the use of the mouse inoculation model. This trial that the search for Toxoplasma gondii in the saliva is not an alternative method for the diagnosis of toxoplasmosis in patients with AIDS.
在弓形虫病患者的唾液中已发现刚地弓形虫。我们试图在艾滋病患者的唾液中分离出寄生虫。众所周知，在巴西，90%或更多的成年人有既往感染刚地弓形虫的血清学证据，因此检测抗弓形虫抗体对诊断艾滋病患者发生的弓形虫病脑脓肿并无帮助。在26例艾滋病患者中，包括6例有影像学证据提示由刚地弓形虫引起脑脓肿的患者，通过小鼠接种模型在其唾液中未发现寄生虫。该试验表明，在艾滋病患者唾液中寻找刚地弓形虫并非诊断弓形虫病的替代方法。
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