Smit D J A, Posthuma D, Boomsma D I, Geus E J C
Department of Biological Psychology, Vrije Universiteit Amsterdam, Amsterdam, The Netherlands.
Psychophysiology. 2005 Nov;42(6):691-7. doi: 10.1111/j.1469-8986.2005.00352.x.
We estimated the genetic and nongenetic (environmental) contributions to individual differences in the background EEG power spectrum in two age cohorts with mean ages of 26.2 and 49.4 years. Nineteen-lead EEG was recorded with eyes closed from 142 monozygotic and 167 dizygotic twin pairs and their siblings, totaling 760 subjects. We obtained power spectra in 24 bins of 1 Hz ranging from 1.0 to 25.0 Hz. Generally, heritability was highest around the alpha peak frequency and lower in the theta and delta bands. In the beta band heritability gradually decreased with increasing frequency, especially in the temporal regions. Genetic correlations between power in the classical broad bands indicated that half to three-quarters of the genetic variance can be attributed to a common source. We conclude that across the scalp and most of the frequency spectrum, individual differences in adult EEG are largely determined by genetic factors.
我们估计了年龄均值分别为26.2岁和49.4岁的两个年龄组中，基因和非基因（环境）因素对背景脑电图功率谱个体差异的影响。对142对同卵双胞胎、167对异卵双胞胎及其兄弟姐妹共760名受试者进行了闭眼状态下的19导联脑电图记录。我们获取了频率范围为1.0至25.0Hz、共24个1Hz频段的功率谱。一般来说，遗传力在α波峰值频率附近最高，在θ波和δ波频段较低。在β波频段，遗传力随频率增加而逐渐降低，尤其是在颞叶区域。经典宽频段功率之间的遗传相关性表明，一半至四分之三的遗传方差可归因于一个共同来源。我们得出结论，在头皮和大部分频谱范围内，成人脑电图的个体差异在很大程度上由遗传因素决定。
