Jain Meenal, Kaur Manmohan
Department of Pathology, Sri Aurobindo Institute of Medical Sciences and Medical College, Indore and Gajra Raja Medical College, Gwalior.
Indian J Pathol Microbiol. 2005 Oct;48(4):464-7.
Quantitative buffy coat (QBC) technique, thick smears, thin smears and conventional buffy coat smears were compared for malarial parasite detection. Of 200 blood samples studied, 70 (35%) samples were positive by QBC technique, 62 (31%) samples by thick smears, 50 (25%) samples by thin smears and only 34 (17%) samples were positive by conventional buffy coat technique. 8 (4%) samples detected by QBC technique alone, had low parasitic index. Haematological analysis was performed on samples positive for malarial parasite. Anaemia was present in 66 (94.28%) samples of which 37 (56.06%) were Plasmodium falciparum, 21 (31.81%) were Plasmodium vivax and 8 (12.12%) had mixed infection (Plasmodium falciparum and Plasmodium vivax). 35 (50%) cases showed normocytic normochromic anaemia. Majority of the samples showed normal total and differential leukocyte count. Thrombocytopenia was found in 49 (70%) samples of which 33 (67.34%) were Plasmodium falciparum.
对定量血沉棕黄层(QBC)技术、厚涂片、薄涂片和传统血沉棕黄层涂片进行疟疾寄生虫检测比较。在研究的200份血样中,QBC技术检测出70份(35%)样本呈阳性,厚涂片检测出62份(31%)样本呈阳性,薄涂片检测出50份(25%)样本呈阳性,而传统血沉棕黄层技术仅检测出34份(17%)样本呈阳性。仅通过QBC技术检测出的8份(4%)样本,其寄生虫指数较低。对疟疾寄生虫呈阳性的样本进行血液学分析。66份(94.28%)样本存在贫血,其中37份(56.06%)为恶性疟原虫,21份(31.81%)为间日疟原虫,8份(12.12%)为混合感染(恶性疟原虫和间日疟原虫)。35例(50%)表现为正细胞正色素性贫血。大多数样本的白细胞总数和分类计数正常。49份(70%)样本发现血小板减少,其中33份(67.34%)为恶性疟原虫。