Handa Uma, Mohan Harsh, Punia Rajpal Singh, Nada Ritambhara
Department of Pathology,Government Medical College, Chandigarh.
Indian J Pathol Microbiol. 2005 Oct;48(4):510-2.
Lymph node infarction is rare and can occur in either nonneoplastic or neoplastic conditions. Fine needle aspiration cytology (FNAC) of infarction preceding lymphoma has not been described earlier. A 26-year-old male, was referred to the cytology laboratory for FNAC of bilateral axillary lymph nodes. FNA smears showed uniform looking ghost cells. There were no viable cells. A biopsy was advised which also showed extensive coagulative necrosis. Five weeks later, right cervical lymph nodes also appeared and FNA smears showed discrete monomorphic population of immature lymphoid cells. A cytologic diagnosis of infarction in a case of non-Hodgkin's lymphoma (NHL) was made and subsequently confirmed by histopathologic examination. Our case indicates that such cases should be followed up closely and repeated aspirations should be done to prevent a delayed diagnosis of lymphoma.
淋巴结梗死很少见，可发生于非肿瘤性或肿瘤性疾病。此前尚未有关于淋巴瘤之前梗死的细针穿刺细胞学检查（FNAC）的报道。一名26岁男性被转诊至细胞学实验室，对双侧腋窝淋巴结进行FNAC检查。细针穿刺涂片显示有外观一致的影细胞。没有活细胞。建议进行活检，活检也显示广泛的凝固性坏死。五周后，右侧颈部淋巴结也出现了，细针穿刺涂片显示有离散的不成熟淋巴细胞单形性群体。做出了非霍奇金淋巴瘤（NHL）病例梗死的细胞学诊断，随后经组织病理学检查证实。我们的病例表明，此类病例应密切随访，并应重复进行穿刺，以防止淋巴瘤的延迟诊断。
