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儿童多发性硬化症与急性播散性脑脊髓炎:难以鉴别的诊断。一名疾病早发小男孩的病例报告

[Multiple sclerosis and acute disseminated encephalomyelitis in children: a difficult diagnostic differentiation. Report of a young boy with early onset of the disease].

作者信息

Vignoli A, Colombo M, Mavilla M, Chiarenza G A, Magni L A

机构信息

Unità Operativa Neuropsichiatria Infantile, Presidio Ospedaliero, Rho (MI).

出版信息

Pediatr Med Chir. 2004 May-Jun;26(3):198-200.

Abstract

We report the case of an eight year old boy who developed suddenly acute left-sided hemiparesis syndrome. Brain magnetic resonance imaging (MRI) showed multiple white matter lesions. Therefore we considered in the differential diagnosis multiple sclerosis (MS) and acute disseminated encephalomyelitis (ADEM). The patient received intravenous immunoglobulin (IVIG), 1 g/kg/d over 2 days with complete regression of clinical symptoms. No relapses occurred within six months, although brain magnetic resonance imaging studies found new white matter lesions, suggesting multiple sclerosis with very early onset.

摘要

我们报告了一例8岁男孩突然出现急性左侧偏瘫综合征的病例。脑部磁共振成像(MRI)显示多处白质病变。因此,在鉴别诊断中我们考虑了多发性硬化症(MS)和急性播散性脑脊髓炎(ADEM)。该患者接受了静脉注射免疫球蛋白(IVIG)治疗,剂量为1 g/kg/天,持续2天,临床症状完全消退。尽管脑部磁共振成像研究发现了新的白质病变,但在六个月内未出现复发,提示为极早期发病的多发性硬化症。

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