Lohr J B, Bracha H S
Department of Psychiatry, School of Medicine, University of California, San Diego.
Am J Psychiatry. 1992 Aug;149(8):1091-5. doi: 10.1176/ajp.149.8.1091.
One piece of genetic evidence for the biological distinctness of schizophrenia and bipolar illness is the rarity of monozygotic twin pairs in which one twin suffers from schizophrenia and the other from bipolar disorder. The authors describe a pair of monozygotic mirror-image twins with discordant diagnoses, schizophrenia in one twin and bipolar or schizoaffective disorder in the other.
精神分裂症和双相情感障碍在生物学上具有独特性的一条遗传学证据是,同卵双胞胎中一个患精神分裂症而另一个患双相情感障碍的情况很罕见。作者描述了一对同卵镜像双胞胎,他们的诊断结果不一致,一个患精神分裂症,另一个患双相情感障碍或分裂情感性障碍。