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采用Dor手术进行左心室重建的患者的室性心动过速手术。

Surgery for ventricular tachycardia in patients undergoing left ventricular reconstruction by the Dor procedure.

作者信息

Sartipy Ulrik, Albåge Anders, Strååt Eva, Insulander Per, Lindblom Dan

机构信息

Department of Cardiothoracic Surgery and Anesthesiology, Karolinska University Hospital, Karolinska Institutet, Stockholm, Sweden.

出版信息

Ann Thorac Surg. 2006 Jan;81(1):65-71. doi: 10.1016/j.athoracsur.2005.06.058.

Abstract

BACKGROUND

Surgical ventricular restoration (the Dor procedure) is an option in patients with coronary artery disease and postinfarction left ventricular aneurysm. The procedure can be extended to treat ventricular tachycardia (VT). The aim of this study was to evaluate the Dor procedure including VT surgery in our institution.

METHODS

From July 1997 to December 2003, 53 consecutive patients with left ventricular aneurysm and VT underwent surgical ventricular restoration including nonguided endocardiectomy and cryoablation. Twenty-four patients had at least one preoperative episode of spontaneous VT, of which 8 were survivors of sudden cardiac death. Twenty-nine patients had inducible-only VT. In 45 patients, who underwent preoperative programmed stimulation, sustained uniform VT could be initiated. Arrhythmia control was evaluated by programmed stimulation or analysis of events registered by implanted defibrillators and by review of patient's records.

RESULTS

Early mortality was 2 of 53 (3.8%). Mean follow-up was 3.7 years. At 1, 3, and 5 years overall actuarial survival was 94%, 80%, and 59%, respectively. Surgical success rate in patients with preoperative spontaneous VT was 91%. Inducible VT was found in 5 of 35 patients who underwent postoperative programmed stimulation. There was no arrhythmia-related late death and there was no loss to follow-up.

CONCLUSIONS

The Dor procedure including VT surgery is an effective treatment for postinfarction left ventricular aneurysm and VT and eliminates the need for an implantable defibrillator in most patients. Early and long-term results are good in terms of survival and arrhythmia control.

摘要

背景

外科心室修复术(Dor手术)是冠心病合并心肌梗死后左心室室壁瘤患者的一种治疗选择。该手术可扩展用于治疗室性心动过速(VT)。本研究的目的是评估我院开展的包括VT手术在内的Dor手术。

方法

1997年7月至2003年12月,53例连续的左心室室壁瘤合并VT患者接受了包括非指导性心内膜切除术和冷冻消融术在内的外科心室修复术。24例患者术前至少有1次自发性VT发作,其中8例为心脏性猝死幸存者。29例患者仅有可诱导性VT。45例接受术前程序刺激的患者可诱发持续性单形性VT。通过程序刺激或分析植入式除颤器记录的事件以及查阅患者病历评估心律失常控制情况。

结果

早期死亡率为53例中的2例(3.8%)。平均随访3.7年。1年、3年和5年的总精算生存率分别为94%、80%和59%。术前有自发性VT的患者手术成功率为91%。35例术后接受程序刺激的患者中有5例发现可诱导性VT。无心律失常相关的晚期死亡,也无失访情况。

结论

包括VT手术在内的Dor手术是治疗心肌梗死后左心室室壁瘤和VT的有效方法,大多数患者无需植入式除颤器。在生存和心律失常控制方面,早期和长期结果良好。

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