Suppr超能文献

固定在聚氨酯泡沫上的东北红豆杉细胞中金属离子和紫杉醇的时空分布。

Spatio-temporal distributions of metal ions and Taxol of Taxus cuspidata cells immobilized on polyurethane foam.

作者信息

Yin De-Ming, Wu Jin-Chuan, Yuan Ying-Jin

机构信息

Department of Pharmaceutical Engineering, School of Chemical Engineering and Technology, Tianjin University, P. O. Box 6888, Tianjin, 300072, PR China.

出版信息

Biotechnol Lett. 2006 Jan;28(1):29-32. doi: 10.1007/s10529-005-4683-4.

Abstract

Distinct spatio-temporal variations of metal ions and Taxol production were observed for Taxus cuspidata cells immobilized on polyurethane foam. The Taxol content in the inner foam layer reached 215 microg g(-1) at day 30, which was 40-fold higher than that in the outer foam layer, and the Ca2+ and Mg2+ contents were 5.3 and 3.7 times higher, while the K+ content was 5.5 times lower. Thus higher intracellular Ca2+ and Mg2+ contents and lower intracellular K+ content may favor the Taxol biosynthesis in immobilized Taxus cuspidata.

摘要

对于固定在聚氨酯泡沫上的东北红豆杉细胞,观察到金属离子和紫杉醇产量存在明显的时空变化。在第30天,泡沫内层的紫杉醇含量达到215微克/克,比外层泡沫层高40倍,Ca2+和Mg2+含量分别高5.3倍和3.7倍,而K+含量低5.5倍。因此,较高的细胞内Ca2+和Mg2+含量以及较低的细胞内K+含量可能有利于固定化东北红豆杉中紫杉醇的生物合成。

相似文献

3
Expression of arabinogalactan proteins involved in Taxol production by immobilized Taxus cuspidata cells.
J Biotechnol. 2008 Jan 1;133(1):96-102. doi: 10.1016/j.jbiotec.2007.09.012.
4
7
Effects of inoculum size and age on biomass growth and paclitaxel production of elicitor-treated Taxus yunnanensis cell cultures.
Appl Microbiol Biotechnol. 2002 Dec;60(4):396-402. doi: 10.1007/s00253-002-1130-5. Epub 2002 Nov 5.
10
Taxol-producing [corrected] fungal endophyte, Pestalotiopsis species isolated from Taxus cuspidata.
J Biosci Bioeng. 2010 Nov;110(5):541-6. doi: 10.1016/j.jbiosc.2010.06.007. Epub 2010 Jul 15.

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验