Muhonen Michael G, Bierman Jeremy S, Hussain Namath S, Hanley Heather A, Hussain Sara S
Department of Surgery, Section of Neurosurgery, Children's Hospital of Orange County, Orange, California, USA.
J Neurosurg. 2005 Aug;103(2 Suppl):180-3. doi: 10.3171/ped.2005.103.2.0180.
Antenatal diagnosis of an intracranial neoplasm is extremely rare. The authors describe a case in which a 21-week-old fetus was found, by using fetal ultrasonography, to have a large intracranial mass. Fetal magnetic resonance (MR) images, obtained at 21 and 25 weeks' gestation, supported the diagnosis of a teratoma. As the tumor increased in size, near-complete brain atrophy ensued. Premature labor was induced, and a nonviable fetus died within minutes of delivery. Postmortem analysis confirmed a teratoma occupying a major portion of the intracranial space. In cases in which abnormal brain development is suspected in a fetus, the use of fetal MR imaging can give a clearer picture of the pathological entity, which may allow for a more accurate diagnosis. The usefulness of fetal MR imaging in monitoring brain development and tumor growth during treatment planning is discussed.
产前诊断颅内肿瘤极为罕见。作者描述了一例通过胎儿超声检查发现一名21周大胎儿颅内有一巨大肿块的病例。在妊娠21周和25周时获得的胎儿磁共振（MR）图像支持畸胎瘤的诊断。随着肿瘤体积增大，继而出现近乎完全的脑萎缩。诱发了早产，一个无法存活的胎儿在分娩后几分钟内死亡。尸检分析证实畸胎瘤占据了颅内空间的大部分。在怀疑胎儿脑发育异常的病例中，使用胎儿磁共振成像可以更清楚地显示病理实体，从而可能做出更准确的诊断。本文还讨论了胎儿磁共振成像在治疗计划中监测脑发育和肿瘤生长的作用。
