Bellas Juan, Hilvarsson Annelie, Granmo Ake
Departamento de Ecoloxía e Bioloxía Animal, Universidade de Vigo, Ctra. Colexio Universitario s/n, Spain.
Biofouling. 2005;21(3-4):207-16. doi: 10.1080/08927010500285236.
Sublethal effects of medetomidine, a new generation antifouling compound, on lumpfish (Cyclopterus lumpus L.) and cod (Gadus morhua L.) larvae were examined. The effects on respiration rate and on colour adaptation of newly hatched larvae were assessed after 24-96 h exposure. Exposure of lumpfish larvae to the experimental concentrations resulted in a significant decrease in respiration rate (Lowest Observed Effect Concentration (LOEC) = 5-10 nM) and in the percentage of dark larvae (LOEC = 4 nM). However, no effects on respiration rate of cod larvae were detected. In addition to lumpfish larvae being affected at low concentrations of medetomidine, a reversibility of the effects was observed when 96 h-exposed larvae were incubated in clean seawater for 24-48 h. Considerations relating to the future commercialisation of medetomidine for antifouling purposes are discussed.
研究了新一代防污化合物美托咪定对太平洋刺狮子鱼（Cyclopterus lumpus L.）和大西洋鳕鱼（Gadus morhua L.）幼鱼的亚致死效应。在暴露24 - 96小时后，评估了对新孵化幼鱼呼吸速率和颜色适应的影响。将太平洋刺狮子鱼幼鱼暴露于实验浓度下，导致呼吸速率显著降低（最低观察效应浓度（LOEC）= 5 - 10 nM）以及深色幼鱼的百分比降低（LOEC = 4 nM）。然而，未检测到对大西洋鳕鱼幼鱼呼吸速率的影响。除了太平洋刺狮子鱼幼鱼在低浓度美托咪定下受到影响外，当暴露96小时的幼鱼在清洁海水中孵育24 - 48小时时，观察到了效应的可逆性。讨论了与美托咪定用于防污目的未来商业化相关的考虑因素。
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