Tedder M, Anstadt M P, Tedder S D, Lowe J E
Department of Surgery, Duke University Medical Center, Durham, NC 27710.
Ann Thorac Surg. 1992 Aug;54(2):387-91. doi: 10.1016/0003-4975(92)91413-4.
The number of patients reported to have undergone bronchoplastic procedures has increased nearly fourfold in the past decade. These techniques represent excellent surgical therapy for patients with benign endobronchial lesions, traumatic airway disruptions, or tumors of low-grade malignant potential, and for select patients with surgically resectable lung cancer. Eighty-nine percent of bronchoplastic procedures are performed for malignancy. We reviewed 1,915 bronchoplastic procedures for carcinoma reported over the past 12 years to determine the incidence of complications and survival. Complications included local recurrence (10.3%), 30-day mortality (7.5%), pneumonia (6.7%), atelectasis (5.4%), benign stricture or stenosis (5.0%), bronchopleural fistulas (3.5%), empyema (2.8%), bronchovascular fistulas (2.6%), and pulmonary embolism (1.9%). Results were further stratified into sleeve lobectomy and sleeve pneumonectomy groups. Five-year survivals for stage I, II, and III carcinoma were 63%, 37%, and 21%, respectively. Sleeve lobectomy for carcinoma extends surgical therapy to select patients with complication rates comparable to pneumonectomy and long-term survival similar to that for conventional resections.
据报告,在过去十年中接受支气管成形手术的患者数量增加了近四倍。这些技术对于患有良性支气管内病变、外伤性气道破裂或低度恶性潜能肿瘤的患者,以及部分可手术切除肺癌的患者而言,是极佳的手术治疗方法。89%的支气管成形手术是针对恶性肿瘤进行的。我们回顾了过去12年报告的1915例针对癌症的支气管成形手术,以确定并发症发生率和生存率。并发症包括局部复发(10.3%)、30天死亡率(7.5%)、肺炎(6.7%)、肺不张(5.4%)、良性狭窄(5.0%)、支气管胸膜瘘(3.5%)、脓胸(2.8%)、支气管血管瘘(2.6%)和肺栓塞(1.9%)。结果进一步分为袖状肺叶切除术和袖状全肺切除术组。I期、II期和III期癌症的五年生存率分别为63%、37%和21%。针对癌症的袖状肺叶切除术将手术治疗扩展到部分患者,其并发症发生率与全肺切除术相当,长期生存率与传统切除术相似。