Lee Sun-Geun, Lee Seung Hyong, Cho Sang-Ho, Song Jae Won, Oh Chang-Mo, Kim Dae Hyun
Department of Thoracic and Cardiovascular Surgery, Kyung Hee University Hospital at Gangdong, Kyung Hee University School of Medicine, Seoul, Korea.
Department of Thoracic and Cardiovascular Surgery, Kyung Hee University Hospital, Kyung Hee University School of Medicine, Seoul, Korea.
J Chest Surg. 2021 Dec 5;54(6):480-486. doi: 10.5090/jcs.21.037.
Although various methods are already used to calculate predicted postoperative forced expiratory volume in 1 second (FEV) based on preoperative FEV in lung surgery, the predicted postoperative FEV is not always the same as the actual postoperative FEV. Observed postoperative FEV values are usually the same or higher than the predicted postoperative FEV. To overcome this issue, we investigated the relationship between the number of resected lung segments and the discordance of preoperative and postoperative FEV values.
From September 2014 to May 2020, the data of all patients who underwent anatomical lung resection by video-assisted thoracoscopic surgery (VATS) were gathered and analyzed retrospectively. We investigated the association between the number of resected segments and the differential FEV (a measure of the discrepancy between the predicted and observed postoperative FEV) using the t-test and linear regression.
Information on 238 patients who underwent VATS anatomical lung resection at Kyung Hee University Hospital at Gangdong and by DH. Kim for benign and malignant disease was collected. After applying the exclusion criteria, 114 patients were included in the final analysis. In the multiple linear regression model, the number of resected segments showed a positive correlation with the differential FEV (Pearson r=0.384, p<0.001). After adjusting for multiple covariates, the differential FEV increased by 0.048 (95% confidence interval, 0.023-0.073) with an increasing number of resected lung segments (R=0.271, p<0.001).
In this study, after pulmonary resection, the number of resected segments showed a positive correlation with the differential FEV.
尽管在肺手术中已采用多种方法根据术前一秒用力呼气容积（FEV）来计算术后预测一秒用力呼气容积，但术后预测FEV并不总是与实际术后FEV相同。观察到的术后FEV值通常与或高于术后预测FEV。为克服这一问题，我们研究了切除肺段数量与术前和术后FEV值不一致之间的关系。
收集并回顾性分析2014年9月至2020年5月期间所有接受电视辅助胸腔镜手术（VATS）进行解剖性肺切除患者的数据。我们使用t检验和线性回归研究切除段数与差异FEV（预测和观察到的术后FEV之间差异的一种度量）之间的关联。
收集了在庆熙大学江东医院由DH. Kim进行的VATS解剖性肺切除治疗良性和恶性疾病的238例患者的信息。应用排除标准后，114例患者纳入最终分析。在多元线性回归模型中，切除段数与差异FEV呈正相关（Pearson r = 0.384，p < 0.001）。在调整多个协变量后，随着切除肺段数量增加，差异FEV增加0.048（95%置信区间，0.023 - 0.073）（R = 0.271，p < 0.001）。
在本研究中，肺切除术后，切除段数与差异FEV呈正相关。
