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在记忆搜索过程中,特定类别皮层活动先于记忆提取出现。

Category-specific cortical activity precedes retrieval during memory search.

作者信息

Polyn Sean M, Natu Vaidehi S, Cohen Jonathan D, Norman Kenneth A

机构信息

Department of Psychology, University of Pennsylvania, Philadelphia, PA 19104, USA.

出版信息

Science. 2005 Dec 23;310(5756):1963-6. doi: 10.1126/science.1117645.

DOI:10.1126/science.1117645
PMID:16373577
Abstract

Here we describe a functional magnetic resonance imaging study of humans engaged in memory search during a free recall task. Patterns of cortical activity associated with the study of three categories of pictures (faces, locations, and objects) were identified by a pattern-classification algorithm. The algorithm was used to track the reappearance of these activity patterns during the recall period. The reappearance of a given category's activity pattern correlates with verbal recalls made from that category and precedes the recall event by several seconds. This result is consistent with the hypothesis that category-specific activity is cueing the memory system to retrieve studied items.

摘要

在此,我们描述了一项针对人类在自由回忆任务中进行记忆搜索的功能磁共振成像研究。通过模式分类算法识别出与三类图片(面部、地点和物体)研究相关的皮质活动模式。该算法用于追踪回忆期间这些活动模式的重现情况。特定类别活动模式的重现与该类别中的言语回忆相关,并且在回忆事件发生前几秒出现。这一结果与特定类别活动提示记忆系统检索已学项目的假设一致。

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