Anscher M S, Prosnitz L R
Duke Comprehensive Cancer Center, Duke University Medical Center, Division of Radiation Oncology, Durham, North Carolina.
Urology. 1992 Jan;39(1):39-43. doi: 10.1016/0090-4295(92)90038-x.
The records of 107 patients with newly diagnosed adenocarcinoma of the prostate irradiated with curative intent at Duke University Medical Center from 1970 through 1983 were reviewed. Forty patients (37%) underwent standard bilateral pelvic lymph node dissection (PLND) prior to beginning irradiation. Twenty-four patients (22%) were found to have pelvic nodal metastases (Stage D1). Those found to have a single microscopically positive node at PLND may be curable with irradiation. In contrast, those with more extensive nodal metastases appear to be incurable with radiotherapy. Additional studies are needed to confirm or refute these findings.
回顾了1970年至1983年在杜克大学医学中心接受根治性放疗的107例新诊断前列腺腺癌患者的记录。40例患者(37%)在开始放疗前接受了标准的双侧盆腔淋巴结清扫术(PLND)。24例患者(22%)被发现有盆腔淋巴结转移(D1期)。那些在PLND中发现单个显微镜下阳性淋巴结的患者可能通过放疗治愈。相比之下,那些有更广泛淋巴结转移的患者似乎无法通过放疗治愈。需要进一步的研究来证实或反驳这些发现。