Chen Xiang-Sheng, Yin Yue-Ping, Liang Guo-Jun, Gong Xiang-Dong, Li Hua-Sheng, Poumerol Gilles, Thuy Nguyen, Shi Mei-Qin, Yu Yan-Hua
National Center for STD and Leprosy Control, 12 Jiangwangmiao Street, Nanjing 210-042, China.
AIDS Patient Care STDS. 2005 Dec;19(12):853-60. doi: 10.1089/apc.2005.19.853.
A cross-sectional prevalence survey of sexually transmitted infections (STIs) was conducted among female sex workers (FSWs) in Kunming, Yunnan Province, China. A total of 505 FSWs participated in the survey. All eligible participants gave informed consent. Demographic, behavioral, and clinical information of the participants was gathered by direct structured interviews. Tampon swabs were collected to test for Chlamydia trachomatis, Nesseria gonorrhoeae, and Trichomonas vaginalis and serum specimens were collected to test for HIV antibody by enzyme-linked immunosorbent assay (ELISA) screening and Western blot confirmation, syphilis with rapid plasma reagin (RPR) and T. pallidum hemagglutination (TPHA) confirmation, and for HSV-2 antibodies with the HerpeSelect 2 ELISA. The most prevalent bacterial STI was Chlamydia trachomatis (58.6%), followed by Trichomonas vaginalis (43.2%) and Neisseria gonorrhoeae (37.8%). Three hundred twenty-seven (65.1%) sex workers had serologic evidence of exposure to HSV-2 infection. Ten percent were positive for HIV infection, all injecting drug users (IDUs); and 9.5% had infection with syphilis. Comprehensive prevention and effective STI services for sex workers and their clients will be the key strategies to the control of STIs, including HIV. Policies and prevention strategies for STI/HIV need to focus on high-risk subpopulations, such as sex workers (particularly sex workers who inject drugs) and their clients.
在中国云南省昆明市的女性性工作者中开展了一项性传播感染（STIs）横断面患病率调查。共有505名女性性工作者参与了此次调查。所有符合条件的参与者均签署了知情同意书。通过直接结构化访谈收集了参与者的人口统计学、行为学和临床信息。采集棉拭子检测沙眼衣原体、淋病奈瑟菌和阴道毛滴虫，采集血清标本通过酶联免疫吸附测定（ELISA）筛查和免疫印迹确认检测HIV抗体，通过快速血浆反应素（RPR）和梅毒螺旋体血凝试验（TPHA）确认检测梅毒，通过HerpeSelect 2 ELISA检测HSV-2抗体。最常见的细菌性性传播感染是沙眼衣原体（58.6%），其次是阴道毛滴虫（43.2%）和淋病奈瑟菌（37.8%）。327名（65.1%）性工作者有HSV-2感染的血清学证据。10%的人HIV感染呈阳性，均为注射吸毒者（IDUs）；9.5%的人感染了梅毒。为性工作者及其客户提供全面预防和有效的性传播感染服务将是控制包括HIV在内的性传播感染的关键策略。性传播感染/艾滋病的政策和预防策略需要关注高危亚人群，如性工作者（特别是注射吸毒的性工作者）及其客户。
