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沙眼衣原体感染在性与生殖健康门诊就诊患者中的研究:中国深圳市宝安区的横断面研究。

Chlamydia trachomatis infection among patients attending sexual and reproductive health clinics: A cross-sectional study in Bao'an District, Shenzhen, China.

机构信息

Shenzhen Baoan Center for Chronic Disease Control, Shenzhen, China.

Shenzhen Center for Chronic Disease Control, Shenzhen, China.

出版信息

PLoS One. 2019 Feb 19;14(2):e0212292. doi: 10.1371/journal.pone.0212292. eCollection 2019.

Abstract

This study aimed to estimate the prevalence of chlamydial trachomatis (CT) infection and explore its risk factors among patients attending sexual and reproductive health clinics in Shenzhen, China. We collected demographic and clinical information from attendees (aged 18-49). CT and Neisseria gonorrhoeae (NG) infection was determined by nucleic acid amplification test (NAAT) on self-collected urine specimens. Of 1,938 participants recruited, 10.3% (95% confidence interval [CI]: 9.6%-11.0%) tested positive for CT. Prevalence was similar between men (10.6% [85/804]; 95% CI, 9.5%-11.7%) and women (10.1% [115/1134]; 95% CI: 9.2%-11.0%). Being 18-25 years old (adjusted odds ratio [aOR] = 2.52; 95%CI:1.35-4.71), never tested for CT before (aOR = 2.42; 95%CI: 1.05-5.61) and infected with NG(aOR = 3.87; 95%CI: 2.10-7.10) were independently associated with CT infection. We found that CT infection is prevalent among patients attending sexual and reproductive health clinics in Shenzhen, China. A comprehensive program including CT screening, surveillance and treatment is urgently needed.

摘要

本研究旨在估计中国深圳性与生殖健康诊所就诊患者中沙眼衣原体(CT)感染的流行率,并探讨其危险因素。我们收集了就诊者(年龄 18-49 岁)的人口统计学和临床信息。通过对自行采集的尿液标本进行核酸扩增试验(NAAT),检测 CT 和淋病奈瑟菌(NG)感染情况。在招募的 1938 名参与者中,10.3%(95%置信区间[CI]:9.6%-11.0%)检测出 CT 阳性。男性(10.6%[85/804];95%CI,9.5%-11.7%)和女性(10.1%[115/1134];95%CI:9.2%-11.0%)的患病率相似。18-25 岁(调整优势比[aOR] = 2.52;95%CI:1.35-4.71)、以前从未检测过 CT(aOR = 2.42;95%CI:1.05-5.61)和感染 NG(aOR = 3.87;95%CI:2.10-7.10)与 CT 感染独立相关。我们发现 CT 感染在中国深圳性与生殖健康诊所就诊患者中较为普遍。迫切需要实施包括 CT 筛查、监测和治疗在内的综合计划。

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