Carod-Artal Francisco Javier
Neurology Department, Sarah Hospital, SMHS, CEP 7330-150, Brasilia DF, Brazil.
Expert Rev Cardiovasc Ther. 2006 Jan;4(1):119-30. doi: 10.1586/14779072.4.1.119.
American trypanosomiasis, known as Chagas disease is a major cause of cardiomyopathy in South America. Irreversible damage to the heart can appear 10-20 years after chagasic infection. The relationship between Chagas cardiomyopathy and ischemic stroke has been reviewed. Significant variables that predict ischemic stroke in chagasic patients have been identified: apical aneurysm, cardiac insufficiency, electrocardiogram arrhythmia and female gender. Chagasic cardiomyopathy should be included in the differential diagnosis of the etiology of stroke, being a potential source of cardioembolic stroke.
美洲锥虫病,即恰加斯病,是南美洲心肌病的主要病因。恰加斯感染后10 - 20年可能会出现不可逆的心脏损伤。关于恰加斯心肌病与缺血性中风之间的关系已有综述。已确定了预测恰加斯病患者缺血性中风的重要变量:心尖动脉瘤、心脏功能不全、心电图心律失常以及女性性别。恰加斯心肌病应纳入中风病因的鉴别诊断,它是心源性栓塞性中风的潜在来源。