使用紧凑型磁共振成像（MRI）对大量受试者进行小梁骨体积分数测量。

Trabecular bone volume fraction measurements of a large number of subjects using a compact MRI.

作者信息

Tomiha Sadanori, Iita Nachiko, Okada Fumi, Furuya Takeshi, Kose Katsumi, Haishi Tomoyuki

机构信息

Institute of Applied Physics, University of Tsukuba, Tsukuba, Ibaraki 305-8573, Japan.

出版信息

Magn Reson Imaging. 2005 Dec;23(10):1011-5. doi: 10.1016/j.mri.2005.10.012.

DOI:10.1016/j.mri.2005.10.012

PMID:16376186

Abstract

Trabecular bone volume fraction (TBVF) and speed of sound (SOS) were measured for the right calcanei of 416 female volunteers. The TBVF was measured with a compact MRI developed in our laboratory. The SOS was measured with a commercial quantitative ultrasound system. It was observed that the correlation coefficient between TBVF and SOS and that between TBVF and age varied depending on the location of region of interest (ROI) in the calcaneus. As a result, an optimum circular ROI with a diameter of 20 mm was determined so that the correlation coefficients were maximized. In the optimum ROI, transverse relaxation time (T2) of the bone marrow protons of the calcaneus was found to be concentrated in a narrow range over the subjects. This result suggested that a 50% scan time reduction in the TBVF measurements could be made by skipping the T2 correction procedure.

摘要

对416名女性志愿者的右侧跟骨测量了小梁骨体积分数（TBVF）和声速（SOS）。TBVF采用我们实验室开发的紧凑型磁共振成像仪进行测量。SOS采用商用定量超声系统进行测量。结果发现，TBVF与SOS之间以及TBVF与年龄之间的相关系数随跟骨感兴趣区域（ROI）的位置而异。因此，确定了一个直径为20 mm的最佳圆形ROI，以使相关系数最大化。在最佳ROI中，发现跟骨骨髓质子的横向弛豫时间（T2）在受试者中集中在一个狭窄的范围内。该结果表明，通过跳过T2校正程序，可将TBVF测量的扫描时间减少50%。