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1例通过嵌合基因检测诊断的肺滑膜肉瘤:影像学表现

A case of pulmonary synovial sarcoma diagnosed with detection of chimera gene: imaging findings.

作者信息

Matsuo Yoshio, Sakai Shuji, Yabuuchi Hidetake, Soeda Hiroyasu, Takahashi Naoki, Okafuji Takashi, Yoshimitsu Kengo, Koga Hirofumi, Yoshino Ichiro, Oda Yoshinao, Nakamura Yuichiro, Honda Hiroshi

机构信息

Department of Clinical Radiology, Graduate School of Medical Sciences, Kyushu University, 3-1-1, Maidashi, Higashi-ku, Fukuoka City, Fukuoka Prefecture 812-8582, Japan.

出版信息

Clin Imaging. 2006 Jan-Feb;30(1):60-2. doi: 10.1016/j.clinimag.2005.07.001.

Abstract

Pulmonary synovial sarcoma is a rare disease, and reports detailing clinicians' radiological findings are few. We report a case of a primary pulmonary synovial sarcoma in a 68-year-old woman. Chest CT revealed a well-defined and homogeneous oval mass measuring 3x2.5 cm in the left lower lobe in contact with the visceral pleura. No pleural effusion was evident. No calcification or fat component was detected. The tumor showed homogeneous hypointensity on both T1- and T2-weighted MR imaging. In this case, a lung metastasis could be excluded with fluorine-18 fluorodeoxyglucose positron emission tomography (FDG-PET), and the final diagnosis was histopathologically confirmed by the chimeric gene detection.

摘要

肺滑膜肉瘤是一种罕见疾病,详细描述临床医生影像学表现的报告较少。我们报告一例68岁女性原发性肺滑膜肉瘤病例。胸部CT显示左肺下叶有一个边界清晰、均匀的椭圆形肿块,大小为3×2.5 cm,与脏层胸膜相连。未见明显胸腔积液。未检测到钙化或脂肪成分。肿瘤在T1加权和T2加权磁共振成像上均表现为均匀低信号。在该病例中,通过氟-18氟脱氧葡萄糖正电子发射断层扫描(FDG-PET)可排除肺转移,最终诊断通过嵌合基因检测得到组织病理学证实。

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