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Mutation in the Bacillus subtilis RNA polymerase beta' subunit confers resistance to lipiarmycin.枯草芽孢杆菌RNA聚合酶β'亚基的突变赋予对脂霉素的抗性。
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2
beta' subunit of bacterial RNA polymerase is responsible for streptolydigin resistance in Bacillus subtilis.细菌RNA聚合酶的β'亚基负责枯草芽孢杆菌对链霉溶菌素的抗性。
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本文引用的文献

1
In vitro activities of OPT-80 and comparator drugs against intestinal bacteria.OPT-80及对照药物对肠道细菌的体外活性。
Antimicrob Agents Chemother. 2004 Dec;48(12):4898-902. doi: 10.1128/AAC.48.12.4898-4902.2004.
2
Structural basis of transcription initiation: an RNA polymerase holoenzyme-DNA complex.转录起始的结构基础：一种RNA聚合酶全酶-DNA复合物
Science. 2002 May 17;296(5571):1285-90. doi: 10.1126/science.1069595.
3
Inhibition by lipiarmycin of bacteriophage growth in Bacillus subtilis.脂霉素对枯草芽孢杆菌中噬菌体生长的抑制作用。
J Virol. 1980 Mar;33(3):945-53. doi: 10.1128/JVI.33.3.945-953.1980.
4
Tiacumicins, a novel complex of 18-membered macrolides. II. Isolation and structure determination.替考米星，一种新型的18元大环内酯类化合物。II. 分离与结构测定。
J Antibiot (Tokyo). 1987 May;40(5):575-88. doi: 10.7164/antibiotics.40.575.
5
In vitro and in vivo evaluation of tiacumicins B and C against Clostridium difficile.替考米星B和C对艰难梭菌的体外和体内评价
Antimicrob Agents Chemother. 1991 Jun;35(6):1108-11. doi: 10.1128/AAC.35.6.1108.
6
Lipiarmycin: an antibiotic inhibiting nucleic acid polymerases.
Biochem Biophys Res Commun. 1975 Mar 3;63(1):328-34. doi: 10.1016/s0006-291x(75)80047-7.
7
Lipiarmycin-resistant ribonucleic acid polymerase mutants of Bacillus subtilis.枯草芽孢杆菌的抗脂臂霉素核糖核酸聚合酶突变体
J Bacteriol. 1977 Oct;132(1):73-9. doi: 10.1128/jb.132.1.73-79.1977.

Mutation in the Bacillus subtilis RNA polymerase beta' subunit confers resistance to lipiarmycin.

作者信息

Gualtieri Maxime, Villain-Guillot Philippe, Latouche Jaqueline, Leonetti Jean-Paul, Bastide Lionel

出版信息

Antimicrob Agents Chemother. 2006 Jan;50(1):401-2. doi: 10.1128/AAC.50.1.401-402.2006.

DOI:10.1128/AAC.50.1.401-402.2006
PMID:16377724
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1346796/
Abstract
摘要