Harbick Kara Hoffman, Sidoti Paul A, Budenz Donald L, Venkatraman Anna, Bruther Megan, Grayson Douglas K, Ko Anne, Yi Glara N
Bascom Palmer Eye Institute, Department of Ophthalmology, University of Miami School of Medicine, Florida, USA.
J Glaucoma. 2006 Feb;15(1):7-12. doi: 10.1097/01.ijg.0000195597.30600.27.
To determine the outcomes of inferonasal Baerveldt glaucoma implant (BGI) surgery.
A retrospective, non-comparative case series of 182 eyes of 182 patients who underwent inferonasal placement of a Baerveldt glaucoma implant. The main outcome measures included intraocular pressure, number of glaucoma medications, best corrected visual acuity, and complications.
Patients were followed for an average (+/- SD) of 19 +/- 15 months. Median Snellen visual acuity was unchanged at last follow-up. Intraocular pressure was reduced from a mean (+/- SD) of 28.6 +/- 11.5 mm Hg preoperatively to 13.4 +/- 5.7 mm Hg at most recent follow-up (P < 0.001). The number of antiglaucoma medications was reduced from a mean (+/- SD) of 2.7 +/- 1.3 preoperatively to 1.1 +/- 1.1 at most recent follow-up. Nineteen eyes met our criteria for failure, yielding a cumulative percent survival of 92% at 12 months, 88% at 24 months, and 77% at 44 months. The most common complications were hyphema (14 eyes, 8%), choroidal effusion (12 eyes, 7%), and corneal decompensation (19 eyes, 10%). Endophthalmitis and diplopia occurred rarely (1 eye, <1%; 3 eyes, 2%, respectively).
Inferonasal Baerveldt glaucoma implant placement appears to be a safe and effective surgical option that may be helpful in certain clinical situations.
确定鼻下象限贝尔维尔德青光眼植入物（BGI）手术的效果。
对182例患者的182只眼进行回顾性、非对照病例系列研究，这些患者接受了鼻下象限贝尔维尔德青光眼植入物植入术。主要观察指标包括眼压、青光眼药物使用数量、最佳矫正视力和并发症。
患者平均随访时间（±标准差）为19±15个月。末次随访时，Snellen视力中位数未变。眼压从术前平均（±标准差）28.6±11.5 mmHg降至最近一次随访时的13.4±5.7 mmHg（P<0.001）。抗青光眼药物使用数量从术前平均（±标准差）2.7±1.3种降至最近一次随访时的1.1±1.1种。19只眼符合我们的失败标准，12个月时累积生存率为92%，24个月时为88%，44个月时为77%。最常见的并发症是前房积血（14只眼，8%）、脉络膜渗漏（12只眼，7%）和角膜失代偿（19只眼，10%）。眼内炎和复视很少发生（分别为1只眼，<1%；3只眼，2%）。
鼻下象限贝尔维尔德青光眼植入物植入术似乎是一种安全有效的手术选择，在某些临床情况下可能有用。
