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使用双巩膜隧道技术评估鼻下艾哈迈德引流阀植入术治疗难治性青光眼的疗效。

Evaluating the outcomes of inferonasal ahmed valve implantation using the double scleral tunnel technique in refractory glaucoma.

作者信息

Asfuroglu Mahmut, Fikret Cenk Zeki

机构信息

Department of Ophthalmology, Ankara Bilkent City Hospital, Ankara, Türkiye.

出版信息

BMC Ophthalmol. 2025 Apr 29;25(1):249. doi: 10.1186/s12886-025-04089-6.

Abstract

BACKGROUND

To evaluate the efficacy and safety of inferonasal quadrant (IN) Ahmed Valve implantation (AVI) using the double scleral tunnel technique in patients who had previously failed glaucoma surgery.

METHODS

This retrospective comparative study included data from 69 patients diagnosed with refractory glaucoma who were followed in a tertiary referral hospital. The IN-AVI group included 35 patients who underwent IN-AVI after failed trabeculectomy or superotemporal quadrant (ST) AVI, and the ST-AVI group included 34 patients who underwent primary ST-AVI. The primary outcome was to analyse the surgical success rate, the secondary outcome was to compare the intraocular pressure (IOP) reduction in the IN-AVI and ST-AVI groups at 1-year postoperatively.

RESULTS

Significant reduction in IOP was observed after IN-AVI at 1-year postoperatively (p < 0.001). The overall success rate was 88.6%. IN-AVI after failed trabeculectomy didn't differ from primary ST-AVI in terms of IOP reduction. IN-AVI after failed ST-AVI showed a lower IOP reduction compared to primary ST-AVI (p = 0.003). No tube exposure was observed at 1-year postoperatively using the double scleral tunnel technique.

CONCLUSIONS

In patients with refractory glaucoma, IN-AVI after failed trabeculectomy was as effective as the primary ST-AVI. Although IN-AVI after failed ST-AVI was effective in reducing IOP, it was significantly less effective than the primary ST-AVI. The prior failure of a trabeculectomy had no impact on the success of AVI. Conversely, a second AVI was less efficacious than the primary AVI.

摘要

背景

评估采用双巩膜隧道技术在下鼻象限(IN)植入艾哈迈德引流阀(AVI)对既往青光眼手术失败患者的疗效和安全性。

方法

这项回顾性比较研究纳入了在一家三级转诊医院接受随访的69例诊断为难治性青光眼患者的数据。IN-AVI组包括35例在小梁切除术或颞上象限(ST)AVI失败后接受IN-AVI的患者,ST-AVI组包括34例接受初次ST-AVI的患者。主要结局是分析手术成功率,次要结局是比较IN-AVI组和ST-AVI组术后1年的眼压(IOP)降低情况。

结果

术后1年IN-AVI后眼压显著降低(p < 0.001)。总体成功率为88.6%。小梁切除术后失败的IN-AVI在眼压降低方面与初次ST-AVI无差异。ST-AVI失败后的IN-AVI与初次ST-AVI相比,眼压降低幅度较小(p = 0.003)。采用双巩膜隧道技术术后1年未观察到引流管暴露。

结论

在难治性青光眼患者中,小梁切除术后失败的IN-AVI与初次ST-AVI效果相同。虽然ST-AVI失败后的IN-AVI在降低眼压方面有效,但明显不如初次ST-AVI有效。小梁切除术先前的失败对AVI的成功没有影响。相反,二次AVI比初次AVI疗效差。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ccf0/12039285/d819a4518889/12886_2025_4089_Fig1_HTML.jpg

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