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主髂动脉内膜切除术:一门失传的技艺?

Aortoiliac endarterectomy: a lost art?

作者信息

Connolly John E, Price Thaine

机构信息

Department of Surgery, University of California, Irvine Medical Center, Irvine, CA 92868, USA.

出版信息

Ann Vasc Surg. 2006 Jan;20(1):56-62. doi: 10.1007/s10016-005-9101-9.

Abstract

Endarterectomy was first performed on a superficial femoral artery in 1946 by Cid dos Santos and subsequently on the abdominal aorta by Wylie in 1951. During the 1950s and 1960s, aortoiliac endarterectomy (AIE) was the standard procedure for treatment of aortoiliac occlusive disease. When prosthetic graft material became available, aortobifemoral bypass (ABFB) replaced AIE in most cases because occlusive disease commonly affects the external iliac arteries also, which were difficult to endarterectomize. As a result, aorto-common iliac endarterectomy became almost a lost art. However, we believe there is still a place for AIE in selected patients based on a review of our results with the procedure. We reviewed 205 patients who survived 10 years after undergoing operation for aortoiliac occlusive disease by either aorto-common iliac endarterectomy (n = 39) or ABFB (n = 166). Ten-year primary patency was 89.2% for AIE and 78% for ABFB. Graft infection or aneurysmal formation occurred in 5% of ABFB and 0% of AIE cases. Ten male patients who underwent AIE for leg and hip claudication with positive penile/brachial indices of </=0.6 enjoyed improvement of erectile dysfunction. Twenty of the 39 AIEs were in female smokers with small vessels, localized disease, and elevated triglycerides. Three patients with end-to-side infected ABFB grafts, two with enteric fistula (one ours, two referred), had their grafts removed, followed by AIE with vein patching of their bypass sites. All three patients survived and at 10-year follow-up had patent reconstructed aortofemoral vessels. Since AIE avoids prosthetic material, it is preferable to ABFB in (1) patients whose aortoiliac occlusive disease does not involve the external iliac arteries; (2) male patients with aortoiliac occlusive disease who, in addition to claudication, have erectile dysfunction with penile/brachial indices of </=0.6 and stenotic internal iliac origins; (3) patients with aortoiliac disease including the external iliac arteries who are not candidates for ABFB because of infection risk or small vessels; (4) patients with localized aortoiliac disease; and (5) patients after removal of an infected ABFB graft (with or without an enteric fistula) that had initially been placed end-to-side for aortoiliac occlusive disease.

摘要

1946年,西德·多斯桑托斯首次在股浅动脉进行了动脉内膜切除术,1951年,怀利随后在腹主动脉进行了该手术。在20世纪50年代和60年代,主髂动脉内膜切除术(AIE)是治疗主髂动脉闭塞性疾病的标准手术。当人工血管材料可用时,在大多数情况下,主股动脉旁路移植术(ABFB)取代了AIE,因为闭塞性疾病通常也会影响髂外动脉,而髂外动脉很难进行动脉内膜切除术。结果,主-总髂动脉内膜切除术几乎失传。然而,根据我们对该手术结果的回顾,我们认为在特定患者中AIE仍有一席之地。我们回顾了205例因主髂动脉闭塞性疾病接受手术且术后存活10年的患者,其中39例行主-总髂动脉内膜切除术(AIE组),166例行ABFB(ABFB组)。AIE组的10年原发性通畅率为89.2%,ABFB组为78%。ABFB组5%的患者发生了移植物感染或动脉瘤形成,AIE组为0%。10例因下肢和臀部间歇性跛行接受AIE手术且阴茎/肱动脉指数≤0.6阳性的男性患者,勃起功能障碍得到改善。39例AIE患者中有20例为女性吸烟者,血管细小,病变局限,甘油三酯升高。3例端侧感染的ABFB移植物患者,2例合并肠瘘(1例为我们治疗的,2例为转诊的),移除了移植物,随后行AIE并对旁路部位进行静脉修补。所有3例患者均存活,10年随访时重建的主股血管通畅。由于AIE避免使用人工材料,因此在以下情况中比ABFB更可取:(1)主髂动脉闭塞性疾病不累及髂外动脉的患者;(2)患有主髂动脉闭塞性疾病的男性患者,除间歇性跛行外,阴茎/肱动脉指数≤0.6且髂内动脉起始部狭窄,伴有勃起功能障碍;(3)因感染风险或血管细小而不适合ABFB的主髂动脉疾病患者,包括累及髂外动脉的患者;(4)主髂动脉疾病局限的患者;(5)最初为治疗主髂动脉闭塞性疾病而行端侧放置的感染ABFB移植物(有或无肠瘘)移除后的患者。

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