Hautmann W, Harms I, Vogel U, Zirngibl A, Wildner M
Bayerisches Landesamt für Gesundheit und Lebensmittelsicherheit, Oberschleissheim.
Gesundheitswesen. 2005 Dec;67(12):853-7. doi: 10.1055/s-2005-858899.
In spring 2004 an accumulation of cases of invasive meningococcal disease was observed in the Allgaeu/Bavaria. Investigations of the isolates showed, that four cases in neighbouring municipalities of the district Oberallgaeu were caused by an identical strain of serogroup C. The particular strain was a rare variant of the so called ET-15 clone, which had caused several outbreaks of severe meningococcal disease among young people in the past, for example in Rottal/Inn (1998), Karlsruhe (1999 - 2000) and Schwerte (2003). The involved health authorities had to decide, which intervention strategies were reasonable and appropriate to the given situation. An epidemiological assessment of the situation was made by the Bavarian Health and Food Safety Authority (LGL) using the recommendations of the permanent immunization committee at the Robert Koch-Institute and of the Advisory Committee on Immunization Practices of the Centers for Disease Control and Prevention (CDC) . The LGL together with the Robert Koch-Institute and the national meningococcal reference centre concluded that the situation fulfilled the criteria for a vaccination indication in accordance with section sign 20 Abs. 5 of the infectious disease control act (Infektionsschutzgesetz, IfSG). On the basis of this assessment the responsible regional health authority issued a public recommendation for vaccination and the district health authority of the Oberallgaeu was assigned to implement a vaccination campaign. The Oberallgaeu health authority offered vaccination sessions to the public in the concerned communities. The target group comprised babies, children, young people and adults up to twenty years, who lived in the concerned communities in the northern part of Oberallgaeu, as well as close contacts of cases and members of the above age group, who had visited communal facilities in the communities concerned. Our report describes the implementation of the vaccination campaign.
2004年春季,在阿尔高/巴伐利亚地区发现了多例侵袭性脑膜炎球菌病病例。对分离菌株的调查显示,上阿尔高地区相邻市镇的4例病例是由血清群C的同一菌株引起的。该特殊菌株是所谓ET-15克隆的罕见变体,过去曾在年轻人中引发过几次严重脑膜炎球菌病疫情,例如在罗塔尔因(1998年)、卡尔斯鲁厄(1999 - 2000年)和施韦特(2003年)。相关卫生当局必须决定哪些干预策略对当前情况是合理且合适的。巴伐利亚卫生与食品安全局(LGL)根据罗伯特·科赫研究所常设免疫委员会以及疾病控制与预防中心(CDC)免疫实践咨询委员会的建议,对该情况进行了流行病学评估。LGL与罗伯特·科赫研究所及国家脑膜炎球菌参考中心得出结论,根据《传染病防治法》(Infektionsschutzgesetz, IfSG)第20条第5款,该情况符合疫苗接种指征标准。基于这一评估,负责的地区卫生当局发布了公开的疫苗接种建议,并指定上阿尔高地区的区卫生当局开展疫苗接种活动。上阿尔高地区卫生当局在相关社区为公众提供了疫苗接种服务。目标群体包括居住在上阿尔高北部相关社区的婴儿、儿童、年轻人以及20岁以下的成年人,还有病例的密切接触者以及上述年龄组中曾到访过相关社区公共设施的人员。我们的报告描述了疫苗接种活动的实施情况。