Herrmann A, Zöller J, Böhler T, Born I A
Klinik und Poliklinik für Mund-Kiefer-Gesichtschirurgie, Heidelberg, Bundesrepublik Deutschland.
Dtsch Zahn Mund Kieferheilkd Zentralbl. 1992;80(2):89-92.
A rare case of chronic granulomatous disease with manifestation in the mandible is presented. A 10-year-old boy showed the clinical picture of osteomyelitis without paresthesia (Vincent syndrome). Diagnosis was done by the nitroblue tetrazolium test (NBT) and by demonstration of a complete cytochrome-b deficiency of the granulocytes. In septic granulomatosis a continuous application of Sulfamethoxazol-Trimetoprim is recommended for prophylaxis of infection. For treatment of infection further antibiotics who pass into the granulocytes like rifampicin and fosfomycin are necessary. Oral surgical procedures request a careful tissue handling and a tight wound closure.
