Meister R, Klempt H W, Most E, Heine J
Med Klin. 1975 Nov 28;70(48):1969-75.
Pulmonary artery and pulmonary wedge pressures were measured at rest and during exercise in 25 young patients with moderate to severe scoliosis. Simultaneous determinations of arterial blood gases and pH were performed. The results of the vascular pressure measurements were compared with those obtained in 15 healthy young subjects. In all patients the pulmonary artery and pulmonary wedge pressure were normal at rest. During mild ergometer exercise, however, an abnormal rise in pulmonary artery pressure occurred in 9 patients. Moreover, an increased diastolic pressure gradient across the pulmonary vascular bed was found in some scoliotic patients indicating an elevated pulmonary vascular resistance. It is supposed that this haemodynamic abnormality is primarily due to a restriction of the pulmonary vascular bed. Relationships between pulmonary artery pressure and arterial oxygen tension and blood pH, respectively, could be found. The possible significance of these results is discussed.
对25例中重度脊柱侧凸的年轻患者在静息和运动状态下测量肺动脉压和肺楔压。同时测定动脉血气和pH值。将血管压力测量结果与15名健康年轻受试者的结果进行比较。所有患者静息时肺动脉压和肺楔压均正常。然而,在轻度测力计运动期间,9例患者出现肺动脉压异常升高。此外,在一些脊柱侧凸患者中发现肺血管床舒张压梯度增加,提示肺血管阻力升高。据推测,这种血液动力学异常主要是由于肺血管床受限所致。分别发现了肺动脉压与动脉血氧张力和血液pH值之间的关系。讨论了这些结果可能的意义。