[吸氧对慢性血栓栓塞性肺动脉高压血流动力学的影响]
[Effect of oxygen inhalation on hemodynamics in chronic thromboembolic pulmonary hypertension].
作者信息
Pitton M B, Düber C, Mayer E, Thelen M
机构信息
Klinik für Radiologie, Johannes Gutenberg-Universität Mainz.
出版信息
Rofo. 1998 Jan;168(1):64-7. doi: 10.1055/s-2007-1015183.
PURPOSE
This study evaluates the haemodynamic effects of oxygen inhalation on pulmonary artery pressure and pulmonary vascular resistance in patients with chronic thromboembolic pulmonary hypertension.
METHOD
In 47 patients with chronic thromboembolic pulmonary hypertension haemodynamic parameters were measured before and after oxygen inhalation.
RESULTS
In moderately severe and severe pulmonary hypertension oxygen inhalation significantly reduced mean pulmonary artery pressure by about 11.1% and 4.6%, respectively. However, pulmonary vascular resistance was not significantly affected. Oxygen saturation improved and heart rate was reduced. Cardiac index decreased in severe pulmonary hypertension. Systemic vascular resistance increased.
CONCLUSION
We conclude that oxygen inhalation reduces pulmonary artery pressure and improves oxygen supply in patients with moderately severe and severe chronic thromboembolic pulmonary hypertension.
目的
本研究评估吸氧对慢性血栓栓塞性肺动脉高压患者肺动脉压和肺血管阻力的血流动力学影响。
方法
对47例慢性血栓栓塞性肺动脉高压患者在吸氧前后测量血流动力学参数。
结果
在中度重度和重度肺动脉高压患者中，吸氧分别使平均肺动脉压显著降低约11.1%和4.6%。然而，肺血管阻力未受到显著影响。氧饱和度改善，心率降低。重度肺动脉高压患者的心指数下降。全身血管阻力增加。
结论
我们得出结论，吸氧可降低中度重度和重度慢性血栓栓塞性肺动脉高压患者的肺动脉压并改善氧供应。
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