Larsson Susanne, Svensson Roger, Gudowska Irena, Ivanchenko Vladimir, Brahme Anders
Department of Medical Radiation Physics, Karolinska Institutet and Stockholm University, P.O. Box 260, S-171 76 Stockholm, Sweden.
Radiat Prot Dosimetry. 2005;115(1-4):503-7. doi: 10.1093/rpd/nci180.
A new thin transmission target technique for fast dose delivery using narrow scanned photon beams has been developed. High-energy, 50-100 MeV, electron beams of low emittance incident on thin low-Z targets produce narrow and intense high-energy bremsstrahlung beams. However, electrons transmitted through the target are bent from the therapeutic beam by a purging magnet and have to be effectively absorbed in a dedicated electron collector. The electron-photon transport through a treatment head has been studied using the Monte Carlo simulation toolkit Geant4. The Geant4 electromagnetic physics processes have been compared with experimental data of radial dose profiles. The differences between calculated and measured radial dose distributions are approximately 2-10%. Preliminary investigations of the collector design have been carried out in order to minimise secondary electron and photon contamination of the therapeutic beam. The toolkit presented here is promising for further development of narrow photon beam therapy.
已经开发出一种新的薄传输靶技术,用于使用窄扫描光子束快速输送剂量。低发射度的50-100 MeV高能电子束入射到薄的低Z靶上,产生窄而强的高能轫致辐射束。然而,穿过靶的电子会被清除磁铁从治疗束中弯曲,并且必须在专用的电子收集器中被有效吸收。使用蒙特卡罗模拟工具包Geant4研究了通过治疗头的电子-光子传输。将Geant4电磁物理过程与径向剂量分布的实验数据进行了比较。计算和测量的径向剂量分布之间的差异约为2-10%。为了最小化治疗束的二次电子和光子污染,已经对收集器设计进行了初步研究。这里介绍的工具包对于窄光子束治疗的进一步发展很有前景。