Chen Xin, Wu Jian-min, Hornischer Klaus, Kel Alexander, Wingender Edgar
Centre of Bioinformatics, College of Life Sciences, National Laboratory of Protein Engineering and Plant Genetic Engineering, Peking University, Beijing 100871, China.
Nucleic Acids Res. 2006 Jan 1;34(Database issue):D104-7. doi: 10.1093/nar/gkj113.
TiProD is a database of human promoter sequences for which some functional features are known. It allows a user to query individual promoters and the expression pattern they mediate, gene expression signatures of individual tissues, and to retrieve sets of promoters according to their tissue-specific activity or according to individual Gene Ontology terms the corresponding genes are assigned to. We have defined a measure for tissue-specificity that allows the user to discriminate between ubiquitously and specifically expressed genes. The database is accessible at http://tiprod.cbi.pku.edu.cn:8080/index.html.
TiProD是一个包含已知某些功能特征的人类启动子序列的数据库。它允许用户查询单个启动子及其介导的表达模式、单个组织的基因表达特征,并根据启动子的组织特异性活性或根据相应基因所归属的单个基因本体术语检索启动子集。我们定义了一种组织特异性度量方法,可让用户区分普遍表达和特异性表达的基因。该数据库可通过http://tiprod.cbi.pku.edu.cn:8080/index.html访问。