Kopp Jürgen, Schwede Torsten
Biozentrum der Universität Basel and Swiss Institute of Bioinformatics, Basel, Switzerland.
Nucleic Acids Res. 2006 Jan 1;34(Database issue):D315-8. doi: 10.1093/nar/gkj056.
The SWISS-MODEL Repository is a database of annotated 3D protein structure models generated by the SWISS-MODEL homology-modelling pipeline. As of September 2005, the repository contained 675,000 models for 604,000 different protein sequences of the UniProt database. Regular updates ensure that the content of the repository reflects the current state of sequence and structure databases, integrating new or modified target sequences, and making use of new template structures. Each Repository entry consists of one or more 3D models accompanied by detailed information about the target protein and the model building process: functional annotation, a detailed template selection log, target-template alignment, summary of the model building and model quality assessment. The SWISS-MODEL Repository is freely accessible at http://swissmodel.expasy.org/repository/.
SWISS-MODEL 资源库是一个由 SWISS-MODEL 同源建模流程生成的带注释的三维蛋白质结构模型数据库。截至 2005 年 9 月，该资源库包含针对 UniProt 数据库中 604,000 个不同蛋白质序列的 675,000 个模型。定期更新可确保资源库的内容反映序列和结构数据库的当前状态，整合新的或修改后的目标序列，并利用新的模板结构。每个资源库条目都由一个或多个三维模型以及有关目标蛋白质和模型构建过程的详细信息组成：功能注释、详细的模板选择日志、目标-模板比对、模型构建总结和模型质量评估。可通过 http://swissmodel.expasy.org/repository/ 免费访问 SWISS-MODEL 资源库。
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