Fok H, Jones B M, Gault D G, Andar U, Hayward R
Craniofacial Centre, Hospital for Sick Children, London.
Br J Plast Surg. 1992 Jul;45(5):394-7. doi: 10.1016/0007-1226(92)90013-n.
Premature fusion of cranial sutures in craniosynostosis has been thought to lead to craniostenosis, which in turn may lead to increased intracranial pressures. In 41 consecutive patients with craniosynostosis, intracranial pressure and intracranial volume were measured. Of the 41 patients, 38 (92.6%) had raised intracranial pressure but only 4 (9.7%) had a decreased skull volume. In the present study, there is no correlation between intracranial volume and intracranial pressure. This study confirms that the measurement of intracranial volume, a non invasive procedure, cannot be used to assess intracranial pressure and to avoid an invasive procedure.
颅缝早闭中颅骨缝的过早融合被认为会导致颅骨狭窄，而这反过来可能会导致颅内压升高。对41例连续性颅缝早闭患者测量了颅内压和颅内体积。在这41例患者中，38例（92.6%）颅内压升高，但只有4例（9.7%）颅骨体积减小。在本研究中，颅内体积与颅内压之间无相关性。本研究证实，作为一种非侵入性操作的颅内体积测量，不能用于评估颅内压以及避免侵入性操作。
