Whittle I R, Johnston I H, Besser M
Surg Neurol. 1984 Apr;21(4):367-72. doi: 10.1016/0090-3019(84)90116-2.
Intracranial pressure changes occurring in patients with craniostenosis were studied by continuous monitoring of intracranial pressure in 20 children. Although clinical or radiologic evidence of intracranial hypertension was present in only one patient, 13 (65%) had persistent or episodic raised intracranial pressure. Intracranial hypertension occurred with involvement of both single and multiple sutures and in four of six patients with hydrocephalus and craniostenosis. Recordings after surgical treatment in nine patients revealed that several months elapsed before intracranial pressure improved significantly or returned to normal, despite apparently adequate bony decompression. This study confirms that continuous monitoring of intracranial pressure adds significantly to clinical assessment in determining the need for, and the efficacy of, surgical treatment in craniostenosis.
通过对20名儿童的颅内压进行连续监测，研究了颅缝早闭患者颅内压的变化。尽管只有1例患者有颅内高压的临床或影像学证据，但13例（65%）存在持续性或间歇性颅内压升高。颅内高压发生于单条和多条颅缝受累的情况，以及6例脑积水合并颅缝早闭患者中的4例。9例患者手术治疗后的记录显示，尽管进行了明显充分的骨性减压，但颅内压在数月后才显著改善或恢复正常。这项研究证实，在确定颅缝早闭手术治疗的必要性和疗效时，颅内压连续监测对临床评估有显著帮助。
