Burzawa-Gérard E, Delevallée-Fortier B
Laboratoire d'Endocrinologie comparée, U.R.A. n. 90, C.N.R.S., Paris.
C R Acad Sci III. 1992;314(9):411-6.
The effect of different preparations of growth hormone (GH) was assayed with 17 beta-estradiol on vitellogenesis in hypophysectomized or normal female silver eels. Vitellogenin (Vg) plasma levels were taken as the index of hepatic vitellogenesis. The E2 doses were chosen to give the same pattern for the plasma Vg level as in the controls. They decreased or remained undetectable in hypophysectomized or normal animals. GH also failed to induce alone a significant modification. When E2 was injected together with a GH, plasma Vg levels were 5.13 +/- 1.30 times higher with salmon GH in hypophysectomized eels and 2.01 +/- 0.25 times higher with bovine GH in normal eels. GH is shown to enhance the effects of E2 on hepatic vitellogenesis induction in a teleost.
在切除垂体的或正常的雌性银鳗中，用17β-雌二醇检测了不同制剂的生长激素（GH）对卵黄发生的影响。以卵黄蛋白原（Vg）血浆水平作为肝脏卵黄发生的指标。选择E2剂量以使其血浆Vg水平模式与对照组相同。在切除垂体的或正常的动物中，它们降低或仍无法检测到。单独使用GH也未能诱导出显著变化。当E2与一种GH一起注射时，切除垂体的鳗鱼中，鲑鱼GH使血浆Vg水平高出5.13±1.30倍，正常鳗鱼中，牛GH使血浆Vg水平高出2.01±0.25倍。结果表明，GH可增强E2对硬骨鱼肝脏卵黄发生诱导的作用。
