Kasthurirangan Sanjeev, Glasser Adrian
College of Optometry, University of Houston, TX 77204, USA.
Vision Res. 2006 Apr;46(8-9):1507-19. doi: 10.1016/j.visres.2005.11.012. Epub 2005 Dec 27.
Age related changes in the dynamics of accommodation (far to near focus) and disaccommodation (near to far focus) are reported in this study. Dynamic responses to step stimulus demands from 1D to 6D, in 1D steps, were recorded with a PowerRefractor in 66 subjects in the age range 14-45 years. The accommodative and disaccommodative responses were fit with exponential functions to calculate response amplitude, time constant and peak velocity. The latency of accommodation did not change and the latency of disaccommodation increased with age. For accommodation, time constant increased and peak velocity decreased with age. For disaccommodation, no change in time constant or peak velocity was found with age. The form of the peak velocity vs response amplitude relationship (main sequence) of accommodation changed with age. The differences in the dynamics of accommodation and disaccommodation with age are discussed with reference to the age related changes in the eye leading to presbyopia.
本研究报告了与年龄相关的调节(从远聚焦到近聚焦)和放松调节(从近聚焦到远聚焦)动态变化。使用PowerRefractor对66名年龄在14至45岁之间的受试者进行记录,这些受试者对从1D到6D、步长为1D的阶跃刺激需求的动态反应。调节和放松调节反应采用指数函数拟合,以计算反应幅度、时间常数和峰值速度。调节的潜伏期没有变化,而放松调节的潜伏期随年龄增长而增加。对于调节,时间常数随年龄增加,峰值速度随年龄降低。对于放松调节,未发现时间常数或峰值速度随年龄变化。调节的峰值速度与反应幅度关系(主序列)的形式随年龄而变化。结合导致老花眼的眼睛与年龄相关的变化,讨论了调节和放松调节动态随年龄的差异。