Foot A B, Oakhill A, Kitchen C
Department of Paediatric Oncology, Royal Hospital for Sick Children, Bristol, England.
Cancer Genet Cytogenet. 1992 Jul 1;61(1):99-100. doi: 10.1016/0165-4608(92)90378-l.
A 7-month-old infant with Klinefelter's syndrome was diagnosed as having acute monoblastic leukemia (AMoL). Chromosome studies of bone marrow at diagnosis showed the karyotype 46,XXY,-Y,t(10;11)(p13;q14). This is the first report of M5A leukemia associated with Klinefelter's syndrome.