伴有47,XY,+X,t(2;10)(q21.1;q26.1)及嗜碱性粒细胞增多的急性单核细胞白血病病例
Case of acute monocytic leukemia with 47,XY,+X,t(2;10)(q21.1;q26.1) and basophilia.
作者信息
Mitev L, Apostolov P, Manolova Y
机构信息
Department of Cytogenetics, Military Medical Academy, Sofia, Bulgaria.
出版信息
Cancer Genet Cytogenet. 1996 Jan;86(1):80-2. doi: 10.1016/0165-4608(95)00056-9.
PMID:8616795
Abstract
The clinical cytogenetic findings of a patient with acute monocytic leukemia with peripheral and bone marrow basophilia are presented. The cytogenetic analysis of bone marrow cells established a pathologic clone with the following unusual karyotype: 47,XY,+X,t(2;10)(q21.1;q26.1). This chromosome abnormality has not been reported previously in leukemic diseases.
摘要
本文报告了一名急性单核细胞白血病患者伴有外周血和骨髓嗜碱性粒细胞增多的临床细胞遗传学结果。对骨髓细胞进行的细胞遗传学分析确定了一个具有以下异常核型的病理克隆：47,XY,+X,t(2;10)(q21.1;q26.1)。这种染色体异常在白血病中此前尚未有报道。
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