Clarkson J
Dental Health Services Research Unit, Dundee Dental Hospital & School, University of Dundee, Dundee, Scotland, UK.
Adv Dent Res. 2005 Dec 1;18(3):39-41. doi: 10.1177/154407370501800302.
There is considerable debate about the feasibility and appropriateness of research in dental primary care, particularly the conduct of clinical trials compared with other research designs. While an evidence-based approach to clinical practice is advocated to improve patient care, research relevant to primary care is sparse, with a gap between research findings and clinical practice. Conducting research in a primary care setting is important, while recruitment and retention methods are crucial for generalizability of the results. Systematic reviews show that high-quality trials provide more reliable outcomes, due to methods such as concealment of allocation to groups, blinding, and particularly outcome assessment and loss to follow-up. Our experience of clinical trials in general dental practice has given insight into the design and conduct that ensure feasibility and generalizability. However, only with adequate funding, good infrastructure, and networks can research be conducted in dental primary care.
关于牙科初级保健研究的可行性和适当性存在相当大的争议，特别是与其他研究设计相比，临床试验的开展。虽然提倡采用循证方法进行临床实践以改善患者护理，但与初级保健相关的研究却很少，研究结果与临床实践之间存在差距。在初级保健环境中开展研究很重要，而招募和保留方法对于结果的可推广性至关重要。系统评价表明，高质量的试验由于采用了诸如分组分配隐藏、盲法等方法，特别是结果评估和失访，能提供更可靠的结果。我们在一般牙科实践中进行临床试验的经验，为确保可行性和可推广性的设计与开展提供了见解。然而，只有具备充足的资金、良好的基础设施和网络，才能在牙科初级保健中开展研究。
