Capelastegui A, España P P, Quintana J M, Areitio I, Gorordo I, Egurrola M, Bilbao A
Service of Pneumology, Hospital de Galdakao, E-48960 Galdakao, Bizkaia, Spain.
Eur Respir J. 2006 Jan;27(1):151-7. doi: 10.1183/09031936.06.00062505.
The CURB-65 score (Confusion, Urea > 7 mmol x L(-1), Respiratory rate > or = 30 x min(-1), low Blood pressure, and age > or = 65 yrs) has been proposed as a tool for augmenting clinical judgement for stratifying patients with community-acquired pneumonia (CAP) into different management groups. The six-point CURB-65 score was retrospectively applied in a prospective, consecutive cohort of adult patients with a diagnosis of CAP seen in the emergency department of a 400-bed teaching hospital from March 1, 2000 to February 29, 2004. A total of 1,100 inpatients and 676 outpatients were included. The 30-day mortality rate in the entire cohort increased directly with increasing CURB-65 score: 0, 1.1, 7.6, 21, 41.9 and 60% for CURB-65 scores of 0, 1, 2, 3, 4, and 5, respectively. The score was also significantly associated with the need for mechanical ventilation and rate of hospital admission in the entire cohort, and with duration of hospital stay among inpatients. The CURB-65 score (Confusion, Urea > 7 mmol x L(-1), Respiratory rate > or = 30 x min(-1), low Blood pressure, and age > or = 65 yrs), and a simpler CRB-65 score that omits the blood urea measurement, helps classify patients with community-acquired pneumonia into different groups according to the mortality risk and significantly correlates with community-acquired pneumonia management key points. The new score can also be used as a severity adjustment measure.
CURB-65评分（意识模糊、尿素>7 mmol/L、呼吸频率≥30次/分钟、低血压、年龄≥65岁）已被提议作为一种辅助临床判断的工具，用于将社区获得性肺炎（CAP）患者分层到不同的管理组。2000年3月1日至2004年2月29日期间，在一家拥有400张床位的教学医院急诊科，对一组前瞻性、连续性的成年CAP诊断患者进行回顾性应用六点CURB-65评分。共纳入1100名住院患者和676名门诊患者。整个队列的30天死亡率随CURB-65评分的增加而直接上升：CURB-65评分为0、1、2、3、4和5时，死亡率分别为0、1.1%、7.6%、21%、41.9%和60%。该评分还与整个队列中机械通气的需求和住院率显著相关，与住院患者的住院时间也显著相关。CURB-65评分（意识模糊、尿素>7 mmol/L、呼吸频率≥30次/分钟、低血压、年龄≥65岁）以及省略血尿素测量的更简单的CRB-65评分，有助于根据死亡风险将社区获得性肺炎患者分类到不同组，并且与社区获得性肺炎管理要点显著相关。新评分还可作为一种严重程度调整指标。
