Malla O K, Karki D B, Byanju R N, Shrestha S
Nepal Eye Hospital, Tripureshwor, Kathmandu.
Kathmandu Univ Med J (KUMJ). 2004 Oct-Dec;2(4):354-9.
Intermediate uveitis affecting pars plana, peripheral retina and underlying choroid affects primarily healthy children and young adults.
To study the components of intermediate uveitis at Nepal Eye Hospital in the year 2003 August to 2004 March.
A prospective study was done in patients with intermediate uveitis visiting Nepal Eye Hospital. Sample size was 50. Specially designed proforma of intermediate uveitis was used to collect particulars of the patients, history, clinical examination findings, investigation reports, management protocols used and the final visual outcome.
Intermediate uveitis was seen more in 20 to 29 years age group (38%) and more prevalent in males (52%). Among the study population farmers constituted maximum proportion (36%) and Mongoloid origin was mostly affected (30%). High number of patients were from the central development region with highest proportion from Dhading district (34%). Anterior segment affection with keratic precipitates and anterior chamber cells were noted in 72% of involved eyes. Vitreous cells were noted in all affected eyes while 4% had vitreous snow banking and 3% had vitreous snow balls. Most of the patients (52%) received between topical steroid and posterior subtenon injection of Triamcinolone. Visual Acuity was improved in 52% of cases and remained static in 46%.while deteriorated in 2%.
Significantly high number of patients with intermediate uveitis has been reported from the central development region mainly from Dhading Kathmandu and Nuwakot districts People in their third decade were found to be commonly involved and Mongloid origin were more commonly affected Anterior chamber spill over was seen in higher percentage of patients than described in literature As the patients presented in milder forms visual acuity improved is of cases with the treatment protocol followed.
累及睫状体扁平部、周边视网膜及下方脉络膜的中间葡萄膜炎主要影响健康儿童和年轻成年人。
研究2003年8月至2004年3月在尼泊尔眼科医院的中间葡萄膜炎患者的构成情况。
对到尼泊尔眼科医院就诊的中间葡萄膜炎患者进行前瞻性研究。样本量为50例。使用专门设计的中间葡萄膜炎表格收集患者的详细信息、病史、临床检查结果、检查报告、所用治疗方案及最终视力结果。
中间葡萄膜炎在20至29岁年龄组中更为常见(38%),男性更为普遍(52%)。在研究人群中,农民占比最大(36%),蒙古人种受影响最多(30%)。大量患者来自中部发展地区,其中来自达丁区的比例最高(34%)。72%的受累眼出现了伴有角膜后沉着物和前房细胞的前段受累情况。所有受累眼均可见玻璃体细胞,4%有玻璃体雪堤,3%有玻璃体雪球。大多数患者(52%)接受了局部类固醇和曲安奈德后Tenon囊下注射联合治疗。52%的病例视力得到改善,46%保持稳定,2%恶化。
据报道,中部发展地区,主要是达丁、加德满都和努瓦科特地区,中间葡萄膜炎患者数量显著增加。发现三十多岁的人最常受累,蒙古人种更易受影响。与文献描述相比,更多患者出现前房炎症蔓延。由于患者病情较轻,按照治疗方案治疗后视力得到改善。