持久性隆起性红斑作为诊断HIV感染的首发临床表现：病例报告
Erythema elevatum diutinum as a first clinical manifestation for diagnosing HIV infection: case history.
作者信息
Rover Patrícia Accioni, Bittencourt Caroline, Discacciati Mariana Pimenta, Zaniboni Mariana Colombini, Arruda Lúcia Helena de Fávaro, Cintra Maria Letícia
机构信息
Dermatology Department, Hospital Universitdrio Celso Pierro (HMCP), Pontifícia Universidade Católica de Campinas (PUC-Campinas), Campinas, São Paulo, Brazil.
出版信息
Sao Paulo Med J. 2005 Jul 7;123(4):201-3. doi: 10.1590/s1516-31802005000400009.
CONTEXT
Erythema elevatum diutinum is a chronic and rare dermatosis that is considered to be a variant of leukocytoclastic vasculitis. It is probably mediated by immune complexes. It is generally associated with autoimmune, neoplastic and infectious processes. Recently, it has been added to the group of specific dermatoses that are associated with HIV.
CASE REPORT
We report on the case of a patient who had erythema elevatum diutinum as the first clinical evidence for diagnosing HIV infection. Dapsone was used in the treatment of this patient, and partial regression of the lesions was achieved within 15 days, even before anti-retroviral therapy was prescribed.
CONCLUSION
When there is a diagnosis of erythema elevatum diutinum, HIV infection should be investigated, especially in atypical and exacerbated clinical manifestations.
背景
持久性隆起性红斑是一种慢性罕见皮肤病，被认为是白细胞破碎性血管炎的一种变体。它可能由免疫复合物介导。通常与自身免疫、肿瘤和感染性疾病相关。最近，它被归入与HIV相关的特定皮肤病类别。
病例报告
我们报告了一例患者，其持久性隆起性红斑是诊断HIV感染的首个临床证据。对该患者使用了氨苯砜治疗，在开始抗逆转录病毒治疗之前，15天内皮损就出现了部分消退。
结论
当诊断为持久性隆起性红斑时，应进行HIV感染调查，尤其是在临床表现不典型和病情加重的情况下。
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