[难治性精神分裂症，残留型：阿立哌唑附加治疗后的症状改善]
[Treatment resistant schizophrenia, residual subtype: symptom improvement after additional treatment with amisulpride].
作者信息
Wolf Karsten, Veismann Stefan, Knecht Guntram, Naber Dieter
机构信息
Universitätsklinikum Hamburg-Eppendorf, Klinik und Poliklinik für Psychiatrie und Psychotherapie.
出版信息
Psychiatr Prax. 2006 Jan;33(1):42-4. doi: 10.1055/s-2003-814854.
BACKGROUND
Therapy resistant, severe residual schizophrenia poses major challenges for the psychiatric pharmacological treatment.
METHOD
We report about a 44-year old schizophrenic male who has been detained in a closed forensic ward for 10 years, following a conviction in one manslaughter case. Despite various pharmacological treatment efforts severe residual schizophrenia remained.
RESULT
Adding Amisulpride to the ongoing treatment with Olanzapine achieved a noticeable improvement of symptoms, resulting in the possibility of relaxing imprisonment conditions.
CONCLUSION
A combination of Amisulpride and Olanzapine seems to be effective in treating severe residual schizophrenia.
背景
难治性、严重残留型精神分裂症给精神科药物治疗带来了重大挑战。
方法
我们报告了一名44岁的男性精神分裂症患者，他因一起 manslaughter 案件被定罪后，被关押在封闭的法医病房10年。尽管进行了各种药物治疗，严重残留型精神分裂症仍然存在。
结果
在正在进行的奥氮平治疗中添加氨磺必利后，症状有了明显改善，从而有可能放宽监禁条件。
结论
氨磺必利和奥氮平联合使用似乎对治疗严重残留型精神分裂症有效。
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