Nishiyama Shinichiro, Momomura Shin-ichi, Ishiwata Sugao, Daida Hiroyuki, Hara Kazuhiro, Nishimura Shigeyuki, Nakamura Masato, Yamashina Akira, Shirai Tetsuro, Yutaro Nishi, Yamazaki Tsutomu
Department of General Internal Medicine, Toranomon Hospital, Kanagawa.
J Cardiol. 2005 Dec;46(6):211-20.
To investigate the quality of life (QOL) of Japanese patients with ischemic heart disease.
The QOL data of 753 patients with chronic and stable ischemic heart disease was assessed using SF-36 Japanese version 1.2 and compared with Japanese national norms. Physical (PCS) and Mental Component Summary (MCS) scores were calculated to examine the correlation with patient background. Patients were also asked about subjective symptoms during the QOL investigation.
Mean age was 63.6 +/- 7.5 years old and the male/female ratio was 85.7/14.3. About one third (30.7%) of the patients were symptomatic and about half (52.6%) had a history of myocardial infarction. Compared to Japanese national norms, physical functioning, role-physical, social functioning, general health and role-emotional were lower, and body pain, vitality and mental health were higher. PCS was significantly lower and MCS was significantly higher in aged patients than in younger patients (p < 0.0001, p < 0.0001). PCS and MCS were significantly lower in the symptom (+) group than in the symptom (-) group (p = 0.0009, p < 0.0001). PCS decreased as the number of anti-angina medications for the patients increased (p = 0.0002). PCS was significantly lower and MCS was significantly higher in the beta blocker (+) group than in the beta blocker (-) group (p < 0.0001, p < 0.03). Multivariate logistic regression analysis showed that age ( > or = 63 years old), symptom (+), duration of disease (> or = 3 years) and beta blocker (+) influenced the QOL.
The QOL level of patients with ischemic heart disease was found to depend on the clinical condition and treatment, so the optimal treatment for ischemic heart disease must be established to improve QOL.
调查日本缺血性心脏病患者的生活质量（QOL）。
使用SF - 36日本版1.2评估753例慢性稳定型缺血性心脏病患者的QOL数据，并与日本全国标准进行比较。计算身体（PCS）和精神成分总结（MCS）得分，以检查与患者背景的相关性。在QOL调查期间，还询问了患者的主观症状。
平均年龄为63.6±7.5岁，男女比例为85.7/14.3。约三分之一（30.7%）的患者有症状，约一半（52.6%）有心肌梗死病史。与日本全国标准相比，身体功能、身体角色、社会功能、总体健康和情感角色较低，而身体疼痛、活力和心理健康较高。老年患者的PCS显著低于年轻患者，MCS显著高于年轻患者（p < 0.0001，p < 0.0001）。症状（+）组的PCS和MCS显著低于症状（ - ）组（p = 0.0009，p < 0.0001）。随着患者抗心绞痛药物数量的增加，PCS降低（p = 0.0002）。β受体阻滞剂（+）组的PCS显著低于β受体阻滞剂（ - ）组，MCS显著高于β受体阻滞剂（ - ）组（p < 0.0001，p < 0.03）。多因素逻辑回归分析表明，年龄（≥63岁）、症状（+）、病程（≥3年）和β受体阻滞剂（+）影响生活质量。
发现缺血性心脏病患者的生活质量水平取决于临床状况和治疗，因此必须确立缺血性心脏病的最佳治疗方法以提高生活质量。
