Fujii Tsukasa, Ogino Satoshi, Arimoto Hiroe, Irifune Morihiro, Iwata Nobuko, Ookawachi Ichiro, Kikumori Hiroshi, Seo Ritsu, Takeda Mariko, Tamaki Akiko, Baba Kenji, Nose Michihiro
Graduate School of Allied Health Sciences, Faculty of Medicine, Osaka University.
Arerugi. 2006 Oct;55(10):1288-94.
The number of patients with Japanese cedar pollinosis (JCP) is increasing, and now, has extended up to about 15% of the Japanese. It is reported that the QOL is an important outcome in the JCP treatment. This study aimed to evaluate the QOL in patients with JCP by means of the SF-8 Health Survey (Japanese Version), a new, even shorter generic health survey.
411 patients with JCP who visited 10 ENT clinics in Osaka from March 14 to March 26 (peak pollen season) were questioned, and 204 patients without any treatments in this season were engaged in this study as subjects. In this study, the QOL scores were evaluated using the SF-8. This is an 8-item version of the SF-36 that yields a comparable 8-dimension health profile and comparable estimates of summary scores for the physical and mental components of health.
The QOL score depressed in the patients with JCP compared with healthy subjects (Japanese national norms). Both Mental Component Score (MCS) and Physical Component Score (PCS) scores decreased more in females than in males. In females, MCS were significantly lower than national norms. The older the patients were, the lower PCS scores were showed. The severity of nasal symptoms influenced the PCS scores.
These results showed the tendency similar to the early studies using SF-36 questionnaire. The sensitivity of SF-8 in the individual is not better than that of other specific QOL questionnaires, but SF-8 can be answered in a short time compared with other questionnaires including SF-36. We suggested that SF-8 become a useful questionnaire in the future.
日本雪松花粉症（JCP）患者数量不断增加，目前已占到日本人口的约15%。据报道，生活质量（QOL）是JCP治疗中的一项重要指标。本研究旨在通过一种新的、更简短的通用健康调查问卷——SF - 8健康调查（日文版），对JCP患者的生活质量进行评估。
对2007年3月14日至3月26日（花粉高峰期）期间前往大阪10家耳鼻喉科诊所就诊的411例JCP患者进行了询问，选取其中204例在该季节未接受任何治疗的患者作为本研究的对象。在本研究中，使用SF - 8评估生活质量得分。这是SF - 36的一个8项版本，可得出类似的8维度健康概况以及对健康的身体和心理组成部分的汇总得分的类似估计值。
与健康受试者（日本全国标准）相比，JCP患者的生活质量得分较低。女性的心理成分得分（MCS）和身体成分得分（PCS）下降幅度均大于男性。在女性中，MCS显著低于全国标准。患者年龄越大，PCS得分越低。鼻部症状的严重程度影响PCS得分。
这些结果显示出与早期使用SF - 36问卷的研究相似的趋势。SF - 8在个体中的敏感性并不优于其他特定的生活质量调查问卷，但与包括SF - 36在内的其他问卷相比，SF - 8可以在短时间内完成作答。我们建议SF - 8在未来成为一种有用的调查问卷。
