Rapid, noninvasive diagnosis of visceral leishmaniasis in India: comparison of two immunochromatographic strip tests for detection of anti-K39 antibody.

作者信息

Sundar Shyam, Maurya Radheshyam, Singh Rakesh K, Bharti K, Chakravarty Jaya, Parekh Ashish, Rai Madhukar, Kumar Kailash, Murray Henry W

机构信息

Kala-Azar Medical Research Center, Department of Medicine, Institute of Medical Sciences, Banaras Hindu University, Varanasi, India.

出版信息

J Clin Microbiol. 2006 Jan;44(1):251-3. doi: 10.1128/JCM.44.1.251-253.2006.

DOI:10.1128/JCM.44.1.251-253.2006

PMID:16390983

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1351954/

Abstract

Used with blood or serum, a new anti-K39 antibody immunochromatographic strip test (IT-Leish; DiaMed AG) proved sensitive (range, 99 to 100%) and specific (range, 95 to 100%) for the noninvasive serodiagnosis of visceral leishmaniasis in India. Used with serum, the IT-Leish test and the existing Kalazar Detect test (InBios International, Inc.) yielded comparable results for symptomatic infection and identified apparent subclinical infection in 15 to 32% of healthy residents in a region where visceral leishmaniasis is highly endemic.

摘要