Sundar Shyam, Maurya Radheshyam, Singh Rakesh K, Bharti K, Chakravarty Jaya, Parekh Ashish, Rai Madhukar, Kumar Kailash, Murray Henry W
Kala-Azar Medical Research Center, Department of Medicine, Institute of Medical Sciences, Banaras Hindu University, Varanasi, India.
J Clin Microbiol. 2006 Jan;44(1):251-3. doi: 10.1128/JCM.44.1.251-253.2006.
Used with blood or serum, a new anti-K39 antibody immunochromatographic strip test (IT-Leish; DiaMed AG) proved sensitive (range, 99 to 100%) and specific (range, 95 to 100%) for the noninvasive serodiagnosis of visceral leishmaniasis in India. Used with serum, the IT-Leish test and the existing Kalazar Detect test (InBios International, Inc.) yielded comparable results for symptomatic infection and identified apparent subclinical infection in 15 to 32% of healthy residents in a region where visceral leishmaniasis is highly endemic.
一种新的抗K39抗体免疫层析试纸条检测(IT - 利什曼病检测;DiaMed AG公司)与血液或血清一起使用时,在印度对内脏利什曼病的非侵入性血清学诊断中显示出高敏感性(范围为99%至100%)和高特异性(范围为95%至100%)。与血清一起使用时,IT - 利什曼病检测和现有的黑热病检测(InBios International公司)对有症状感染产生了可比的结果,并在一个内脏利什曼病高度流行地区15%至32%的健康居民中发现了明显的亚临床感染。